MINOCA biomarkers: Non-atherosclerotic aspects

被引：5
|
作者：
Xu, Xiaojian [1 ]
Zhang, Guoliang [1 ]
Li, Zhaoqing [1 ]
Li, Daisong [1 ]
Chen, Ruolan [1 ]
Huang, Chao [1 ]
Li, Yonghong [1 ]
Li, Bing [2 ,3 ]
Yu, Haichu [1 ]
Chu, Xian-Ming [1 ,4 ]
机构：
[1] Qingdao Univ, Affiliated Hosp, Dept Cardiol, Qingdao 266100, Peoples R China
[2] Qingdao Univ, Basic Med Coll, Dept Genet & Cell Biol, Qingdao 266000, Peoples R China
[3] Qingdao Univ, Affiliated Hosp, Dept Hematol, Qingdao 266000, Peoples R China
[4] Qingdao Univ, Affiliated Cardiovasc Hosp, Qingdao 266071, Peoples R China
来源：
CLINICA CHIMICA ACTA | 2023年 / 551卷
基金：
中国国家自然科学基金;
关键词：
MINOCA; Biomarkers; Mechanisms; Diagnosis; Prognosis; Therapeutic targets; CORONARY-ARTERY DISSECTION; ACUTE MYOCARDIAL-INFARCTION; ADIPOSE-TISSUE INFLAMMATION; FIBROMUSCULAR DYSPLASIA; MICROVASCULAR DYSFUNCTION; ENDOTHELIAL DYSFUNCTION; VASOSPASTIC ANGINA; KINASE ACTIVITY; POSITION PAPER; RISK-FACTORS;
D O I：
10.1016/j.cca.2023.117613
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Myocardial infarction in the absence of obstructive coronary artery disease (MINOCA) is an important subtype of myocardial infarction. Although comprising less than 50% stenosis in the main epicardial coronary arteries, it constitutes a severe health risk. A variety of approaches have been recommended, but definitive diagnosis remains elusive. In addition, the lack of a comprehensive understanding of underlying pathophysiology makes clinical management difficult and unpredictable. This review highlights ongoing efforts to identify relevant biomarkers in MINOCA to improve diagnosis, individualize treatment and better predict outcomes.
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页数：13
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