The sensitivity of mTORC1 signaling activation renders tissue regenerative capacity

被引：0

作者：

Dou, Hanyu ^{[1
,2
]}

Li, Jianzhou ^{[1
,2
]}

Huang, Taomin ^{[3
]}

Ding, Xiaolei ^{[1
,2
,4
]}

机构：

[1] Shanghai Univ, Affiliated Nantong Hosp, Inst Geriatr, Peoples Hosp Nantong 6,Sch Med, Nantong 226011, Peoples R China

[2] Shanghai Univ, Shanghai Engn Res Ctr Organ Repair, Shanghai 200444, Peoples R China

[3] Fudan Univ, Eye & ENT Hosp, Dept Pharm, Shanghai 200031, Peoples R China

[4] Fudan Univ, Huashan Hosp, Dept Dermatol, Shanghai, Peoples R China

来源：

CELL REGENERATION | 2023年 / 12卷 / 01期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1186/s13619-023-00183-6

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

A better understanding of how and why the regenerative capacity differs among species will not only provide insights into the regeneration process but also hold value for the development of regenerative medicine and the improvement of healing procedures. In a recent Nature article, Zhulyn et al. identify a critical role played by the activation of mechanistic target of rapamycin complex 1 (mTORC1) signaling in enhancing tissue regenerative capacity in animals.

引用

页数：4

共 50 条

[1] The sensitivity of mTORC1 signaling activation renders tissue regenerative capacity
Hanyu Dou
Jianzhou Li
Taomin Huang
Xiaolei Ding
Cell Regeneration, 12
[2] Connecting mTORC1 signaling to SREBP-1 activation
Bakan, Inan
Laplante, Mathieu
CURRENT OPINION IN LIPIDOLOGY, 2012, 23 (03) : 226 - 234
[3] Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK
Zhou, Hongyu
Shang, Chaowei
Wang, Min
Shen, Tao
Kong, Lingmei
Yu, Chunlei
Ye, Zhennan
Luo, Yan
Liu, Lei
Li, Yan
Huang, Shile
BIOCHEMICAL PHARMACOLOGY, 2016, 116 : 39 - 50
[4] Inhibition of mTORC1 renders cardiac protection against lipopolysaccharide
Li, Xiang
Jiang, Lijing
Lin, Shenghui
He, Yunfen
Shen, Guofeng
Cai, Zhenlin
Ling, Meirong
Ni, Jindi
Zhang, Hao
Zhang, Min
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2014, 7 (12): : 8432 - 8442
[5] Recent advances in understanding of amino acid signaling to mTORC1 activation
Zhuang, Yu
Wang, Xiang-xiang
He, Jieyu
He, Shanping
Yin, Yulong
FRONTIERS IN BIOSCIENCE-LANDMARK, 2019, 24 : 971 - 982
[6] Key mediators of intracellular amino acids signaling to mTORC1 activation
Duan, Yehui
Li, Fengna
Tan, Kunrong
Liu, Hongnan
Li, Yinghui
Liu, Yingying
Kong, Xiangfeng
Tang, Yulong
Wu, Guoyao
Yin, Yulong
AMINO ACIDS, 2015, 47 (05) : 857 - 867
[7] Activation of mTORC1 Signaling Pathway in AIDS-Related Lymphomas
El-Salem, Mouna
Raghunath, Puthiyaveettil N.
Marzec, Michal
Liu, Xiaobin
Kasprzycka, Monika
Robertson, Erle
Wasik, Mariusz A.
AMERICAN JOURNAL OF PATHOLOGY, 2009, 175 (02): : 817 - 824
[8] Gαq activation modulates autophagy by promoting mTORC1 signaling
Cabezudo, Sofia
Sanz-Flores, Maria
Caballero, Alvaro
Tasset, Inmaculada
Rebollo, Elena
Diaz, Antonio
Aragay, Anna M.
Cuervo, Ana Maria
Mayor Jr, Federico
Ribas, Catalina
NATURE COMMUNICATIONS, 2021, 12 (01)
[9] Rheb/mTORC1 Signaling Promotes Kidney Fibroblast Activation and Fibrosis
Jiang, Lei
Xu, Lingling
Mao, Junhua
Li, Jianzhong
Fang, Li
Zhou, Yang
Liu, Wei
He, Weichun
Zhao, Allan Zijian
Yang, Junwei
Dai, Chunsun
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2013, 24 (07): : 1114 - 1126
[10] Key mediators of intracellular amino acids signaling to mTORC1 activation
Yehui Duan
Fengna Li
Kunrong Tan
Hongnan Liu
Yinghui Li
Yingying Liu
Xiangfeng Kong
Yulong Tang
Guoyao Wu
Yulong Yin
Amino Acids, 2015, 47 : 857 - 867

← 1 2 3 4 5 →