Reconfigurable subsampling mixer-first RF front-end is a potential candidate for low-power applications as it operates at a low clock frequency and hence consumes low power. However, the subsampling down-conversion has not been employed in mixer-first RF front-ends due to the disadvantage of high noise figure from inherent noise folding and lack of RF port impedance matching because of nonzero IF down-conversion. To address the above two issues, first, a subsampling multipath down-conversion mixer scheme is proposed for rejecting 3 f(s)/4 and 5 f(s)/4 down-conversions, thereby alleviating the effect of noise folding, leading to low noise figure. Second, an IF-stage impedance matching scheme is proposed that provides 50 Omega matching at the RF port of the mixer using an IF-LNA in shunt with an M-phase switch-capacitor filter. The analysis of the proposed scheme in terms of noise figure, conversion gain, and harmonic rejection is presented. The proposed subsampling mixer-first RF front-end is implemented in 1.2 V, 65-nm CMOS technology. The prototype occupies an active area of 0.33 mm(2), the switch-capacitor mixer and M-phase filter consume 400 mu W of power, and IF amplifier and nonoverlapping clock generation circuit consume 25 mW and 6-12.6 mW of power, respectively. The RF front-end achieves a 6.5-dB noise figure, 15.1-dB conversion gain, 50-dB harmonic rejection ratio (HRR), and +10-dBm IB-IIP3.