Study of Epigenetic Modifications of Nucleic Acids Based on Supramolecular Chemistry

Nucleic acids are the genetic material of living organisms and play important roles in the living system. In addition to the classical bases, there are also naturally modified bases in nucleic acids, which are called epigenetic modifications of nucleic acids. Epigenetic modifications of nucleic acids play an important role in the regulation of gene expression and have a great impact on the genetic and growth processes of organisms, and the nucleic acid epigenetics are closely associated to diseases as well. Supramolecular chemistry study the intermolecular bonds, and many biomolecules perform their biological functions via supramolecular processes, and it can be said that a large number of supramolecular chemical processes naturally exist in living organisms. This paper highlighted some repre-sentative work on epigenetic modification of nucleic acids based on supramolecular chemistry.