The Roman Republic of Letters. Scholarship, Philosophy, and Politics in the Age of Cicero and Caesar.

被引:0
|
作者
Kumar, Kundan [1 ]
Das, Ashish [1 ,2 ]
Prasad, Shashi Bhushan [1 ]
机构
[1] Natl Inst Technol, Dept Prod & Ind Engn, Jamshedpur, Jharkhand, India
[2] Natl Inst Technol, Dept Prod & Ind Engn, North Annexe Room NA03, Jamshedpur 831014, Jharkhand, India
关键词
Mg-Hopeite composite; biodegradability; bioactive; orthopedic implant applications; FSP; ORTHOPEDIC IMPLANT APPLICATIONS; MATRIX COMPOSITES; CORROSION BEHAVIOR; WEAR CHARACTERIZATION; MECHANICAL-PROPERTIES; MAGNESIUM ALLOY; STAINLESS-STEEL; PURE MAGNESIUM; FRICTION; MICROSTRUCTURE;
D O I
10.1177/09544119231158837
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Magnesium (Mg) shows excellent potential for orthopedic implant applications owing to its equivalent mechanical prop-erties compared to cortical bone and its biocompatibility. However, the rapid degradation rate of magnesium and its alloys in the physiological environment results in losing their mechanical integrity before complete bone healing. In light of this, friction stir processing (FSP), a solid-state process, is used to fabricate Hopeite (Zn(PO4)(2).4H(2)O) reinforced novel magnesium composite. As a result of the novel composite fabricated by FSP, grain refinement of the matrix phase occurs significantly. The samples were immersed in simulated body fluid (SBF) for in-vitro bioactivity and biodegradability tests. The corrosion behavior of pure Mg, FSP Mg, and FSP Mg-Hopeite composite samples was compared using electro-chemical and immersion tests in SBF. It found that Mg-Hopeite composite has better corrosion resistance than FSP Mg and pure Mg. Because of grain refinement and the presence of secondary phase Hopeite in the composite, the mechani-cal properties and corrosion resistance improved. The bioactivity test was performed in the SBF environment, and a rapid apatite layer was formed on the surface of Mg-Hopeite composite samples during the test. Osteoblast-like MG63 cells were exposed to samples, and the MTT assay confirmed the non-toxicity of the FSP Mg-Hopeite composite. The wettability of the Mg-Hopeite composite was improved than pure Mg. The present research findings showed that the novel Mg-Hopeite composite fabricated by FSP is a promising candidate for orthopedic implant applications, unreported in the literature.
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页码:502 / 516
页数:15
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