Distance-based microfluidic assays for instrument-free visual point-of-care testing

被引:15
|
作者
Khan, Mashooq [1 ,2 ]
Zhao, Binglu [1 ,2 ]
Wu, Wenli [1 ,2 ]
Zhao, Mei [1 ,2 ]
Bi, Yanhui [1 ,2 ]
Hu, Qiongzheng [1 ,2 ]
机构
[1] Qilu Univ Technol, Shandong Acad Sci, Shandong Anal & Test Ctr, Jinan 250014, Peoples R China
[2] Qilu Univ Technol, Shandong Acad Sci, Sch Pharmaceut Sci, Jinan 250014, Peoples R China
基金
中国国家自然科学基金;
关键词
Microfluidic; Point-of-care devices; Diagnosis; Immunoassays; Biomarkers; PAPER ANALYTICAL DEVICE; SELF-ASSEMBLED MONOLAYERS; LABEL-FREE; LOW-COST; QUANTITATIVE DETECTION; SENSITIVE DETECTION; MASS-SPECTROMETRY; FABRICATION; QUANTIFICATION; SENSOR;
D O I
10.1016/j.trac.2023.117029
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The increasing numbers of diseases due to food toxins, environmental changes and industrial outputs necessitate the development of a simple, fast, and low-cost technology for monitoring biofluids and environmental samples. The distance-based microfluidic analytical sensors (d -mu AS), which rely on dis-tance as a readout signal, offer the advantages of simplicity, being portable, eco-friendly, instrument-free, low-cost, and rapid detection time. Also, it is significant in a setup with limited resources and a lack of skilled personnel. The present review focuses on the progress in substrate preparation, application, advantages, challenges, and future directions of d -mu AS. This review will interest the researchers and explore methods for developing high-quality biosensors and their applications in advanced engineering processes.(c) 2023 Elsevier B.V. All rights reserved.
引用
收藏
页数:18
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