Organization of vestibular circuits for postural control in zebrafish

Most animals begin controlling their posture, or orientation with respect to gravity, at an early stage in life. Posture is vital for locomotor function. Even animals like fish, which are capable of swimming upside-down, must actively control their orientation to coordinate behaviors such as capturing prey near the water's surface. Here we review recent research from multiple laboratories investigating the organization and function of the vestibular circuits underlying postural control in zebrafish. Some findings in zebrafish strongly align with prior observations in mammals, reinforcing our understanding of homologies between systems. In other instances, the unique transparency and accessibility of zebrafish has enabled new analyses of several neural circuit components that remain challenging to study in mammalian systems. These new results demonstrate topographical and circuit features in postural control. timing demonstrate development sensing The from These