Implantable biomedical materials for treatment of bone infection

被引：9

作者：

Shuaishuai, Wang ^{[1
]}

Tongtong, Zhu ^{[1
]}

Dapeng, Wang ^{[2
]}

Mingran, Zhang ^{[1
]}

Xukai, Wang ^{[1
]}

Yue, Yu ^{[1
]}

Hengliang, Dong ^{[1
]}

Guangzhi, Wu ^{[1
]}

Minglei, Zhang ^{[1
]}

机构：

[1] Jilin Univ, Dept Orthoped, China Japan Union Hosp, Changchun, Peoples R China

[2] Siping Cent Hosp, Dept Orthoped, Siping, Peoples R China

来源：

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY | 2023年 / 11卷

关键词：

biological materials; bone infection; multifunctional material; implantable material; treatment of bone infection; progress of infection treatment; multifunctionalization of materials; MESOPOROUS BIOACTIVE GLASS; CALCIUM-PHOSPHATE; ANTIBACTERIAL PROPERTIES; DRUG-DELIVERY; IN-VITRO; SILVER; COATINGS; CHITOSAN; BIOCOMPATIBILITY; VANCOMYCIN;

D O I：

10.3389/fbioe.2023.1081446

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The treatment of bone infections has always been difficult. The emergence of drug-resistant bacteria has led to a steady decline in the effectiveness of antibiotics. It is also especially important to fight bacterial infections while repairing bone defects and cleaning up dead bacteria to prevent biofilm formation. The development of biomedical materials has provided us with a research direction to address this issue. We aimed to review the current literature, and have summarized multifunctional antimicrobial materials that have long-lasting antimicrobial capabilities that promote angiogenesis, bone production, or "killing and releasing. " This review provides a comprehensive summary of the use of biomedical materials in the treatment of bone infections and a reference thereof, as well as encouragement to perform further research in this field.

引用

页数：19

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