Present and Future Prospects of the Anti-cancer Activities of Saikosaponins

被引：3

作者：

Xiao, Li-Xia ^{[1
]}

Zhou, Hui-Nian ^{[2
]}

Jiao, Zuo-Yi ^{[2
]}

机构：

[1] Lanzhou Univ, Coll Clin Med 2, Lanzhou, Peoples R China

[2] Lanzhou Univ Second Hosp, Dept Gen Surg, Lanzhou, Peoples R China

来源：

CURRENT CANCER DRUG TARGETS | 2023年 / 23卷 / 01期

关键词：

Saikosaponin A; saikosaponin B; saikosaponin C; saikosaponin D; cancer; MDR; D INHIBITS PROLIFERATION; MEDIATED MULTIDRUG-RESISTANCE; HEPATOMA-CELLS; RADIX-BUPLEURI; CANCER CELLS; SIGNALING PATHWAY; PROSTATE-CANCER; D SUPPRESSES; D INCREASES; IN-VITRO;

D O I：

10.2174/1568009622666220806121008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Since their discovery, saikosaponins (SSs) have been found to play an important role in treating a variety of cancers via diverse mechanisms of action. This review summarizes the current research status and prospects of the anti-cancer activities of SSs, providing novel insights into the limitations of current studies. In addition, it discusses whether SSs can be applied in immunotherapy and the possible mechanisms by which SSs may facilitate immunotherapy. The research is significant to understanding the anti-cancer potents of SSs in the development of SSs-based therapeutic strategies and clinical practice.

引用

页码：2 / 14

页数：13

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