Objective: To evaluate the efficacy of focused extracorporeal shockwave therapy for symptoms and function in patients with moderate-to-severe carpal tunnel syndrome. Design: A single-blind randomized controlled trial. Subjects: Twenty-four outpatients with moderateto-severe carpal tunnel syndrome. Methods: Patients were randomly allocated into 2 groups: a focused extracorporeal shockwave therapy group and a control group. The focused extracorporeal shockwave therapy group received conservative treatment in addition to focused extracorporeal shockwave therapy with an energy flux density ranging from 0.01 to 0.15 mJ/mm2, a frequency of 4-5 Hz, and 1500 pulses per session once a week for a total of 3 sessions. The control group received only conservative treatment, which comprised gliding exercises for carpal tunnel syndrome, a night wrist splint, and lifestyle modification. The Thai version of the Boston Carpal Tunnel Questionnaire (T-BCTQ), a nerve conduction study, and ultrasonography of the median nerve cross-sectional area were performed before treatment and at 3 and 6 weeks after baseline. Results: The T-BCTQ symptom and function scores had significantly decreased in both groups, favouring focused extracorporeal shockwave therapy at all time-points. In addition, distal sensory and motor latency were significantly different between the groups at 3 weeks from baseline. Conclusion: Focused extracorporeal shockwave therapy plus conservative treatment effectively provided short-term improvement in symptoms, hand function, and nerve conduction in patients with moderate-to-severe carpal tunnel syndrome compared with conservative treatment alone.
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Kerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Kerman Univ Med Sci, Fac Tradit Med, Dept Persian Med, Kerman, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Farzadkia, Mohammad
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Tajadini, Haleh
Ahmadi, Amir Moghadam
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Thomas Jefferson Univ, Philadelphia, PA USAKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Ahmadi, Amir Moghadam
Dahesh, Tania
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Kerman Univ Med Sci, Sch Publ Hlth, Dept Biostat & Epidemiol, Kerman, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Dahesh, Tania
Setayesh, Mohammad
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Kerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Kerman Univ Med Sci, Fac Tradit Med, Dept Persian Med, Kerman, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran