SAFETY AND EFFICACY OF UPADACITINIB FOR PEDIATRIC PATIENTS WITH POLYARTICULAR COURSE JUVENILE IDIOPATHIC ARTHRITIS: AN INTERIM ANALYSIS OF AN OPEN-LABEL, PHASE 1 TRIAL

被引：4

作者：

Brunner, H. ^{[1
]}

Horneff, G. ^{[2
,3
]}

Foeldvari, I. ^{[4
]}

Anton, J. ^{[5
]}

Mohamed, M. E. ^{[6
]}

Qian, Y. ^{[6
]}

Unnebrink, K. ^{[7
]}

Hao, S. ^{[6
]}

Camp, H. ^{[6
]}

Khan, N. ^{[6
]}

Shmagel, A. ^{[6
]}

机构：

[1] Univ Cincinnati, Cincinnati Childrens Hosp Med Ctr, Rheumatol, Cincinnati, OH USA

[2] Asklepios Clin Sankt Augustin, Gen Pediat, St Augustin, Germany

[3] Univ Hosp Cologne, Paediat & Adolescents Med, Cologne, Germany

[4] Klinikum Eilbek, Hamburger Zentrum Kinder & Jugendrheumatol, Hamburg, Germany

[5] Univ Barcelona, Hosp Sant Joan Deu, Pediat Rheumatol, Barcelona, Spain

[6] AbbVie, Rheumatol, N Chicago, IL USA

[7] AbbVie Deutschland GmbH & Co KG, Rheumatol, Ludwigshafen, Germany

来源：

ANNALS OF THE RHEUMATIC DISEASES | 2023年 / 82卷

关键词：

Clinical Trials; Safety; Outcome measures;

D O I：

10.1136/annrheumdis-2023-eular.3987

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：108 / 109

页数：2

共 50 条

[1] PHARMACOKINETICS OF UPADACITINIB IN PEDIATRIC PATIENTS WITH POLYARTICULAR COURSE JUVENILE IDIOPATHIC ARTHRITIS
Qian, Y.
Shmagel, A.
Hao, S.
Horneff, G.
Brunner, H.
Camp, H.
Liu, W.
Mohamed, M. E.
ANNALS OF THE RHEUMATIC DISEASES, 2023, 82 : 666 - 667
[2] Efficacy and Safety of Tocilizumab for Polyarticular-Course Juvenile Idiopathic Arthritis in the Open-Label Two-Year Extension of a Phase III Trial
Brunner, Hermine I.
Ruperto, Nicolino
Zuber, Zbigniew
Cuttica, Ruben
Keltsev, Vladimir
Xavier, Ricardo M.
Burgos-Vargas, Ruben
Penades, Inmaculada Calvo
Silverman, Earl D.
Espada, Graciela
Zavaler, Manuel Ferrandiz
Kimura, Yukiko
Duarte, Carolina
Job-Deslandre, Chantal
Joos, Rik
Douglass, Wendy
Wimalasundera, Sunethra
Bharucha, Kamal N.
Wells, Chris
Lovell, Daniel J.
Martini, Alberto
de Benedetti, Fabrizio
ARTHRITIS & RHEUMATOLOGY, 2021, 73 (03) : 530 - 541
[3] Pharmacokinetic and safety profile of tofacitinib in children with polyarticular course juvenile idiopathic arthritis: results of a phase 1, open-label, multicenter study
Nicolino Ruperto
Hermine I. Brunner
Zbigniew Zuber
Nikolay Tzaribachev
Daniel J. Kingsbury
Ivan Foeldvari
Gerd Horneff
Elzbieta Smolewska
Richard K. Vehe
Anasuya Hazra
Rong Wang
Charles A. Mebus
Christine Alvey
Manisha Lamba
Sriram Krishnaswami
Thomas C. Stock
Min Wang
Ricardo Suehiro
Alberto Martini
Daniel J. Lovell
Pediatric Rheumatology, 15
[4] Pharmacokinetic and safety profile of tofacitinib in children with polyarticular course juvenile idiopathic arthritis: results of a phase 1, open-label, multicenter study
Ruperto, Nicolino
Brunner, Hermine I.
Zuber, Zbigniew
Tzaribachev, Nikolay
Kingsbury, Daniel J.
Foeldvari, Ivan
Horneff, Gerd
Smolewska, Elzbieta
Vehe, Richard K.
Hazra, Anasuya
Wang, Rong
Mebus, Charles A.
Alvey, Christine
Lamba, Manisha
Krishnaswami, Sriram
Stock, Thomas C.
Wang, Min
Suehiro, Ricardo
Martini, Alberto
Lovell, Daniel J.
PEDIATRIC RHEUMATOLOGY, 2017, 15
[5] Open-label phase 3 study of intravenous golimumab in patients with polyarticular juvenile idiopathic arthritis
Ruperto, Nicolino
Brunner, Hermine, I
Pacheco-Tena, Cesar
Louw, Ingrid
Vega-Cornejo, Gabriel
Spindler, Alberto J.
Kingsbury, Daniel J.
Schmeling, Heinrike
Borzutzky, Arturo
Cuttica, Ruben
Inman, C. J.
Malievskiy, Victor
Scott, Christiaan
Keltsev, Vladimir
Terreri, Maria Teresa
Viola, Diego Oscar
Xavier, Ricardo M.
Fernandes, Taciana A. Pedrosa
Velazquez, Maria Del Rocio Maldonado
Henrickson, Michael
Clark, Michael B.
Bensley, Karen A.
Li, Xiaoming
Lo, Kim Hung
Leu, Jocelyn H.
Hsu, Chyi-Hung
Hsia, Elizabeth C.
Xu, Zhenhua
Martini, Alberto
Lovell, Daniel J.
RHEUMATOLOGY, 2021, 60 (10) : 4495 - 4507
[6] Subcutaneous Abatacept in Patients With Polyarticular-Course Juvenile Idiopathic Arthritis Results From a Phase III Open-Label Study
Brunner, Hermine, I
Tzaribachev, Nikolay
Vega-Cornejo, Gabriel
Louw, Ingrid
Berman, Alberto
Calvo Penades, Inmaculada
Anton, Jordi
Avila-Zapata, Francisco
Cuttica, Ruben
Horneff, Gerd
Foeldvari, Ivan
Keltsev, Vladimir
Kingsbury, Daniel J.
Oscar Viola, Diego
Joos, Rik
Lauwerys, Bernard
Paz Gastanaga, Maria Eliana
Elena Rama, Maria
Wouters, Carine
Bohnsack, John
Breedt, Johannes
Fischbach, Michel
Lutz, Thomas
Minden, Kirsten
Mirava, Tatiana
Ally, Mahmood M. T. M.
Rubio-Perez, Nadina
Gervais, Elisabeth Solau
Van Zyl, Riana
Li, Xiaohui
Nys, Marleen
Wong, Robert
Banerjee, Subhashis
Lovell, Daniel J.
Martini, Alberto
Ruperto, Nicolino
ARTHRITIS & RHEUMATOLOGY, 2018, 70 (07) : 1144 - 1154
[7] Intravenous abatacept in Japanese patients with polyarticular-course juvenile idiopathic arthritis: results from a phase III open-label study
Ryoki Hara
Hiroaki Umebayashi
Syuji Takei
Nami Okamoto
Naomi Iwata
Yuichi Yamasaki
Yasuo Nakagishi
Toshitaka Kizawa
Ichiro Kobayashi
Tomoyuki Imagawa
Noriko Kinjo
Norihito Amano
Yoko Takahashi
Masaaki Mori
Yasuhiko Itoh
Shumpei Yokota
Pediatric Rheumatology, 17
[8] Intravenous abatacept in Japanese patients with polyarticular-course juvenile idiopathic arthritis: results from a phase III open-label study
Hara, Ryoki
Umebayashi, Hiroaki
Takei, Syuji
Okamoto, Nami
Iwata, Naomi
Yamasaki, Yuichi
Nakagishi, Yasuo
Kizawa, Toshitaka
Kobayashi, Ichiro
Imagawa, Tomoyuki
Kinjo, Noriko
Amano, Norihito
Takahashi, Yoko
Mori, Masaaki
Itoh, Yasuhiko
Yokota, Shumpei
PEDIATRIC RHEUMATOLOGY, 2019, 17 (1)
[9] Long-term open-label preliminary study of the safety and efficacy of leflunomide in patients with polyarticular-course juvenile rheumatoid arthritis
Silverman, E
Spiegel, L
Hawkins, D
Petty, R
Goldsmith, D
Schanberg, L
Duffy, C
Howard, P
Strand, V
ARTHRITIS AND RHEUMATISM, 2005, 52 (02): : 554 - 562
[10] EFFICACY AND SAFETY OF TOCILIZUMAB IN PATIENTS WITH POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS: DATA FROM A PHASE 3 TRIAL
De Benedetti, F.
Ruperto, N.
Zuber, Z.
Keane, C.
Harari, O.
Kenwright, A.
Cuttica, R.
Keltsev, V.
Xavier, R.
Calvo, I.
Nikishina, I.
Rubio-Perez, N.
Alekseeva, E.
Chasnyk, V.
Chavez, J.
Horneff, G.
Opoka-Winiarska, V.
Quartier, P.
Silva, C.
Silverman, E.
Spindler, A.
Martini, A.
Lovell, D.
Brunner, H.
ANNALS OF THE RHEUMATIC DISEASES, 2013, 72 : 70 - 70

← 1 2 3 4 5 →