Comparing Substance Use Consequences between Serotonergic Psychedelics, MDMA, and other Drugs of Abuse Among United States Adults with History of Psychiatric Illness

被引:1
|
作者
Black, Joshua C. [1 ]
Schow, Nicole [1 ]
Burkett, Hannah L. [1 ]
Pena, Morgan [1 ]
Jewell, Jennifer S. [1 ]
Czizik, Annika [1 ]
Monte, Andrew A. [1 ,2 ]
Dart, Richard C. [1 ,2 ]
机构
[1] Denver Hlth & Hosp Author, Rocky Mt Poison & Drug Safety, 1391 N Speer Blvd,600,M-C 0180, Denver, CO 80204 USA
[2] Univ Colorado, Sch Med, Dept Emergency Med, Aurora, CO USA
关键词
Psychedelics; MDMA; Psilocybin; Psychiatric illness; LSD; US population; PSILOCYBIN; DISORDER; EXPERIENCES; PREVALENCE; RESPONSES;
D O I
10.1007/s11469-023-01163-2
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Psychedelic-assisted therapy could transform treating psychiatric illness, but harms from exacerbating substance use disorder (SUD) among adults with psychiatric illness using psychedelics have not been studied. A cross-sectional survey in the US was used to test whether Drug Abuse Screening Test scores (DAST-10, validated instrument predicting SUD) were more severe when psychiatric illnesses (anxiety disorder, major depressive disorder [MDD], post-traumatic stress disorder [PTSD], and bipolar disorder) and serotonergic psychedelic or MDMA use were combined. Any psychedelic use among adults with psychiatric illness history (anxiety: 5.1% [95% CI: 4.7, 5.6]; MDD: 5.1% [4.3, 5.8]; PTSD: 6.9% [5.9, 7.9]; bipolar: 9.2% [8.0, 10.5]) was more prevalent than the general population (2.6% [2.5, 2.8]). Significant increases in scores were associated with psychedelic use independent of other concurrent drug use, but increases were smaller than for opioids or stimulants. Approaches to managing SUD risks with psychedelics should differ from past approaches for other drugs.
引用
收藏
页码:1179 / 1192
页数:14
相关论文
共 18 条
  • [1] Gender Differences in Psychiatric and Behavioral Health Burden Among Adults With Alcohol and Other Substance Use Disorders in the United States
    Rhee, Taeho Greg
    Rosenheck, Robert A.
    JOURNAL OF ADDICTION MEDICINE, 2022, 16 (03) : 295 - 302
  • [2] Use of mental health and substance abuse treatment services among adults with HIV in the United States
    Burnam, MA
    Bing, EG
    Morton, SC
    Sherbourne, C
    Fleishman, JA
    London, AS
    Vitiello, B
    Stein, M
    Bozzette, SA
    Shapiro, MF
    ARCHIVES OF GENERAL PSYCHIATRY, 2001, 58 (08) : 729 - 736
  • [3] Posttraumatic Stress Disorder Mediating Associations Between Child Sexual Abuse and Substance Use Among Transgender Adults in the United States
    Laughney, Caitlin I.
    Lee, Yong Gun
    Paine, Emily Allen
    Wu, Elwin
    AMERICAN JOURNAL OF ORTHOPSYCHIATRY, 2025, 95 (01) : 45 - 51
  • [4] Screening for psychiatric disorders among adults presenting for substance use disorder treatment: Current practices in the United States
    Maisto S.A.
    Kivlahan D.
    International Journal of Mental Health and Addiction, 2008, 6 (1) : 32 - 36
  • [5] The relationship of history of psychiatric and substance use disorders on risk of dementia among racial and ethnic groups in the United States
    Aranda, Maria P.
    Liang, Jiaming
    Wang, Xinhui
    Schneider, Lon S.
    Chui, Helena C.
    FRONTIERS IN PSYCHIATRY, 2023, 14
  • [6] PREVALENCE, CORRELATES, AND SUBSTANCE USE AND PSYCHIATRIC PREDICTORS OF REGULARLY DRINKING ALCOHOL BEFORE SEX AMONG ADULTS IN THE UNITED STATES
    Eaton, N. R.
    Thompson, R. G.
    Hu, M.
    Hasin, D. S.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2015, 39 : 194A - 194A
  • [7] The Relationship Between Discrimination and Substance Use Disorders Among Lesbian, Gay, and Bisexual Adults in the United States
    McCabe, Sean Esteban
    Bostwick, Wendy B.
    Hughes, Tonda L.
    West, Brady T.
    Boyd, Carol J.
    AMERICAN JOURNAL OF PUBLIC HEALTH, 2010, 100 (10) : 1946 - 1952
  • [8] Psychiatric Treatment and Repeat Suicide Attempts Among Adults With Substance Use, by HIV Status, United States, 2014-2020
    Iqbal, Shareen A.
    Truman, Benedict, I
    Crosby, Alex E.
    PUBLIC HEALTH REPORTS, 2023, 138 (05) : 796 - 805
  • [9] Patterns of tobacco use and tobacco-related psychiatric morbidity and substance use among middle-aged and older adults in the United States
    Blazer, Dan G.
    Wu, Li-Tzy
    AGING & MENTAL HEALTH, 2012, 16 (03) : 296 - 304
  • [10] Prevalence, sociodemographic correlates and DSM-5 substance use disorders and other psychiatric disorders among sexual minorities in the United States
    Kerridge, Bradley T.
    Pickering, Roger P.
    Saha, Tulshi D.
    Ruan, W. June
    Chou, S. Patricia
    Zhang, Haitao
    Jung, Jeesun
    Hasin, Deborah S.
    DRUG AND ALCOHOL DEPENDENCE, 2017, 170 : 82 - 92