Cardiovascular considerations in management of patients with Turner syndrome

被引:5
|
作者
Stefil, Maria [1 ,2 ,3 ]
Kotalczyk, Agnieszka [1 ,2 ,4 ]
Blair, Joanne C. [1 ,3 ]
Lip, Gregory Y. H. [1 ,2 ,4 ,5 ]
机构
[1] Univ Liverpool, Liverpool Ctr Cardiovasc Sci, Liverpool, England
[2] Liverpool Heart & Chest Hosp NHS Fdn Trust, Liverpool, England
[3] Alder Hey Childrens NHS Fdn Trust, Dept Endocrinol, Liverpool, England
[4] Med Univ Silesiaia, Silesian Ctr Heart Dis, Dept Cardiol Congenital Heart Dis & Electrotherap, Zabrze, Poland
[5] Aalborg Univ, Dept Clin Med, Aalborg Thrombosis Res Unit, Aalborg, Denmark
关键词
GROWTH-HORMONE TREATMENT; CONGENITAL HEART-DISEASE; GH-TREATED GIRLS; TERM-FOLLOW-UP; BLOOD-PRESSURE; REPLACEMENT THERAPY; CLINICAL-PRACTICE; YOUNG-WOMEN; AORTIC DIMENSIONS; DIABETES-MELLITUS;
D O I
10.1016/j.tcm.2021.12.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Turner syndrome (TS) is a chromosomal disorder that affects 25-50 per 10 0,0 0 0 live born females. Patients with TS face a heavy burden of cardiovascular disease (congenital and acquired) with an increased risk of mortality and morbidity compared to the general population. Cardiovascular diseases are a major cause of death in females with TS. Approximately 50% of TS patients have a congenital heart abnormality, with a high incidence of bicuspid aortic valve, coarctation of the aorta and generalised arteriopathy. Frequently, females with TS have systemic hypertension, which is also a risk factor for progressive cardiac dysfunction and aortopathy. This paper aims to provide an overview of the cardiovascular assessment, management and follow up strategies in this high-risk population.(c) 2021 Elsevier Inc. All rights reserved.
引用
收藏
页码:150 / 158
页数:9
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