An Update on Orthobiologics: Cautious Optimism

被引:3
|
作者
Nelson, Patrick A. [1 ,2 ]
George, Tom [1 ,3 ]
Bowen, Edward [1 ,4 ]
Sheean, Andrew J. [1 ,5 ]
Bedi, Asheesh [1 ,3 ]
机构
[1] Univ Chicago & Northshore Univ Healthcare Syst, Chicago, IL USA
[2] Univ Chicago, Dept Orthoped Surg, 5841 S Maryland Ave,MC 3079, Chicago, IL 60637 USA
[3] Northshore Univ Healthcare Syst, Chicago, IL USA
[4] Weill Cornell Med, New York, NY USA
[5] San Antonio Mil Med Ctr, Dept Orthoped Surg, San Antonio, TX USA
来源
AMERICAN JOURNAL OF SPORTS MEDICINE | 2024年 / 52卷 / 01期
关键词
orthobiologics; platelet-rich plasma; PRP; MSC; stem cell; BMAC; PLATELET-RICH PLASMA; MESENCHYMAL STROMAL CELLS; MIDPORTION ACHILLES TENDINOPATHY; AUTOLOGOUS PROTEIN SOLUTION; RANDOMIZED CONTROLLED-TRIAL; BONE-MARROW ASPIRATE; ROTATOR CUFF REPAIR; STEM-CELLS; GROWTH-FACTOR; MENISCAL REPAIR;
D O I
10.1177/03635465231192473
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Orthobiologics are rapidly growing in use given their potential to augment healing for multiple musculoskeletal conditions. Orthobiologics consist of a variety of treatments including platelet-rich plasma and stem cells that provide conceptual appeal in providing local delivery of growth factors and inflammation modulation. The lack of standardization in nomenclature and applications within the literature has led to a paucity of high-quality evidence to support their frequent use. The purpose of this review was to describe the current landscape of orthobiologics and the most recent evidence regarding their use.
引用
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页码:242 / 257
页数:16
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