Multisystem Inflammatory Syndrome in Children Among Persons Who Completed a Two-dose COVID-19 Vaccine Primary Series Compared With Those Reporting No COVID-19 Vaccination, US National MIS-C Surveillance

被引:4
|
作者
Yousaf, Anna R. [1 ,4 ]
Miller, Allison D. [1 ]
Lindsey, Katherine [1 ,2 ]
Shah, Ami B. [1 ,3 ]
Wu, Michael J. [1 ]
Melgar, Michael [1 ]
Zambrano, Laura D. [1 ]
Campbell, Angela P. [1 ,4 ]
机构
[1] CDC, Coronavirus & Other Resp Viruses Div, Atlanta, GA USA
[2] 4ES Corp, San Antonio, TX USA
[3] Gen Dynam Informat Technol, Fairfax, VA USA
[4] CDCP, Coronavirus & Other Resp Viruses Div, 1600 Clifton Rd NE, MS-H24-9, Atlanta, GA 30329 USA
关键词
MIS-C; COVID-19; children; vaccine; IMMUNIZATION PRACTICES; ADVISORY-COMMITTEE; UNITED-STATES;
D O I
10.1097/INF.0000000000004103
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We analyzed multisystem inflammatory syndrome in children cases by reported COVID-19 vaccination status (2-dose primary series vs. no vaccination). A total of 46% vaccinated versus 58% unvaccinated persons received intensive care unit-level care (P = 0.02); the risk of intensive care unit admission was 23% higher (adjusted relative risk: 1.23; 95% confidence interval: 1.03-1.48) among unvaccinated patients; 21 unvaccinated persons died. Multisystem inflammatory syndrome in children occurs after SARS-CoV-2 infection in vaccinated persons, but may be less severe.
引用
收藏
页码:E476 / E478
页数:3
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