Computational studies of micron particle deposition is used to predict inhaled particles through the nasal cavity for understanding drug delivery or toxicology risks. To ensure reliable results in future studies, this study evaluated particle tracking schemes and determined the most appropriate settings for predicting micron particle deposition in a pipe bend and nasal cavity geometry. Micron particles were injected into a fully developed 90 degrees pipe bend under a turbulent flow regime with Reynolds number, Re = 10,000, for comparison with existing data in the literature. Similarly, the micron particles were released into a more complex geometry, a human nasal cavity. The study found that although the high-resolution tracking is the default and preferred option set out by Ansys-Fluent, the 5 mu m particle tested travelled further than when the highresolution tracking was off. This was rectified by setting the wall nodal velocity to zero. All particle tracking schemes performed well and were suitable for predicting deposition for particle diameters > 5 mu m, with high-resolution tracking and setting the wall nodal velocity to zero. However, the results become sensitive to the particle scheme when dealing with particle diameters < 5 mu m. The lower-order schemes overpredict deposition, while the higher-order schemes have zero deposition in the pipe bend unless the wall nodal velocity is set to zero. This study provides a list of recommended settings to best simulate particle deposition efficiency in Ansys Fluent (version 2023R2), although future releases of the CFD software may incorporate these settings as default options.
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Center for Air Resources Engineering and Science, Clarkson University, Potsdam, NY, United StatesCenter for Air Resources Engineering and Science, Clarkson University, Potsdam, NY, United States
Wang, Zuocheng
Hopke, Philip K.
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Center for Air Resources Engineering and Science, Clarkson University, Potsdam, NY, United StatesCenter for Air Resources Engineering and Science, Clarkson University, Potsdam, NY, United States
Hopke, Philip K.
Ahmadi, Goodarz
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Center for Air Resources Engineering and Science, Clarkson University, Potsdam, NY, United StatesCenter for Air Resources Engineering and Science, Clarkson University, Potsdam, NY, United States
Ahmadi, Goodarz
Cheng, Yung-Sung
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Lovelace Respiratory Research Institute, Albuquerque, NM, United StatesCenter for Air Resources Engineering and Science, Clarkson University, Potsdam, NY, United States
Cheng, Yung-Sung
Baron, Paul A.
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National Institute for Occupational Safety and Health, Cincinnati, OH, United StatesCenter for Air Resources Engineering and Science, Clarkson University, Potsdam, NY, United States
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Macquarie Univ, Fac Sci & Engn, Sch Engn, Sydney, NSW 2109, AustraliaMacquarie Univ, Fac Sci & Engn, Sch Engn, Sydney, NSW 2109, Australia
Cai, Xinyu
Milton-McGurk, Liam
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Macquarie Univ, Fac Sci & Engn, Sch Engn, Sydney, NSW 2109, Australia
Univ Sydney, Sch Aerosp Mech & Mechatron Engn, Sydney, NSW 2006, AustraliaMacquarie Univ, Fac Sci & Engn, Sch Engn, Sydney, NSW 2109, Australia
Milton-McGurk, Liam
Chan, Hak-Kim
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Univ Sydney, Fac Med & Hlth, Sydney Pharm Sch, Adv Drug Delivery Grp, Sydney, NSW, AustraliaMacquarie Univ, Fac Sci & Engn, Sch Engn, Sydney, NSW 2109, Australia
机构:
Univ Autonoma Metropolitana Azcapotzalco UAM A, Dept Ciencias Basicas, Av San Pablo 180, Mexico City 02200, DF, MexicoUniv Autonoma Metropolitana Azcapotzalco UAM A, Dept Ciencias Basicas, Av San Pablo 180, Mexico City 02200, DF, Mexico
Sigalotti, Leonardo Di G.
Alvarado-Rodriguez, Carlos E.
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Direcc Catedras CONACYT, Av Insurgentes Sur 1582, Mexico City 03940, DF, Mexico
Univ Guanajuato, Dept Ingn Quim, DCNyE, Noria Alta S-N, Guanajuato 36000, MexicoUniv Autonoma Metropolitana Azcapotzalco UAM A, Dept Ciencias Basicas, Av San Pablo 180, Mexico City 02200, DF, Mexico
Alvarado-Rodriguez, Carlos E.
Klapp, Jaime
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Inst Nacl Invest Nucl ININ, Carretera Mexico Toluca Km 36-5, La Marquesa 52750, Ocoyoacac, MexicoUniv Autonoma Metropolitana Azcapotzalco UAM A, Dept Ciencias Basicas, Av San Pablo 180, Mexico City 02200, DF, Mexico
Klapp, Jaime
Cela, Jose M.
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Barcelona Supercomp Ctr BSC CNS, Campus Nord UPC, Barcelona 08034, SpainUniv Autonoma Metropolitana Azcapotzalco UAM A, Dept Ciencias Basicas, Av San Pablo 180, Mexico City 02200, DF, Mexico
机构:
Lovelace Respiratory Research Institute, P.O. Box 5890, Albuquerque, NM 87185-5890, United StatesLovelace Respiratory Research Institute, P.O. Box 5890, Albuquerque, NM 87185-5890, United States
Zwartz, G.J.
Smuin, S.R.
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University of Iowa, Biomedical Engineering, 1042 Engineering Building, Iowa City, IA 52242, United StatesLovelace Respiratory Research Institute, P.O. Box 5890, Albuquerque, NM 87185-5890, United States
Smuin, S.R.
Guilmette, R.A.
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Lovelace Respiratory Research Institute, P.O. Box 5890, Albuquerque, NM 87185-5890, United StatesLovelace Respiratory Research Institute, P.O. Box 5890, Albuquerque, NM 87185-5890, United States