Direct decoration of commercial cotton fabrics by binary nickel-cobalt metal-organic frameworks for flexible glucose sensing in next-generation wearable sensors

Having a prime significance in diagonsing and predicting the dangerous symptoms of chronic diseases in the early stages, special attention has been drawn by wearable glucose-sensing platforms in recent years. Herein, modified commercial cotton fabrics, decorated with binary Ni-Co metal-organic frameworks (NC-MOFs) through a one-pot scalable hydrothermal route, were directly utilized as flexible electrodes for non-enzymatic glucose amperometric sensing. Glucose sensitivities of 105.2 mu A mM(-1) cm(-2) and 23 mu A mM(-1) cm(-2) were acheived within two distinct linear dynamic ranges of 0.04-3.13 mM and 3.63-8.28 mM, respectively. Receiving benefits from a remarkable glucose sensitivity behavior in co-existence of iso-structures and interferences, rapid response (4.2 s), and remarkable reproducibility and repeatability, NC-MOF-modified cotton fabric electrodes are imensilly promising for developing high-performance wearable glucose sensing platfroms. The sensing performance of fabricated electrodes was further investigated in human blood serum and saliva.