Supersensitive Detection of Vibrio Cholera Using Novel Graphene-based Optical Device Based on a Surface Plasmon Resonance Structure

Vibrio cholera (V.C.) is currently one of the most hazardous bacteria since it can lead to hepatitis, diarrhea, vomiting, and typhoid. The various methodologies include time-consuming steps that take several hours before the test report is accessible. Therefore, creating a quick and reliable technique to identify V.C. is essential. The detection of V.C. is proposed in this study using a unique bio-photonic detector that employs Surface Plasmon Resonance (SPR) structure and layers of silver (Ag), silicon (Si), and graphene (G). The reflectance spectrum properties are inspected by the transfer matrix technique. To optimize the efficiency of the bio-photonic sensor, the effects of changing the type of prism and layer thicknesses are thoroughly examined. The proposed detector achieves an extremely great sensitivity of 307.81 Deg./RIU as the structure has Ag (50 nm), Si (3 nm), and the G monolayer, which is not obtained in many previous studies in this sector. The suggested detector also facilitates designing for industry using low-cost product nanofabrication methods due to its low cost, customizable design and straightforward structure. Based on these benefits, the suggested detector candidate is a practical and effective device for detecting V.C. in water, and it may also be used for any biological sample. The optical device designed based on the proposed sensor can be used for detecting V.C and used in biomedical applications.