BackgroundSacrococcygeal pilonidal sinus is a common surgical condition that requires various treatment options. This study aims to investigate the short and long-term outcomes of the modified Karydakis flap method in patients with sacrococcygeal pilonidal sinus.MethodsA retrospective analysis was conducted on 175 patients who underwent the modified Karydakis flap method for sacrococcygeal pilonidal sinus by a single surgeon between September 2015 and February 2021. The patients' demographics, operative time, hospitalization time and complications were recorded.ResultsOf the 175 patients, 125 (71.43%) were male and 50 (28.57%) were female, with a mean age of 24.93 +/- 10.27 years. The mean operative time was 55.05 +/- 12.33 min, the follow-up time was 39.21 +/- 17.58 months, and the mean hospitalization time was 3.4 +/- 1.65 days. Complications were observed in 12 (6.85%) patients, including seroma (5.14%) and wound infection (1.71%), with no observed cases of flap necrosis or recurrence.ConclusionThe modified Karydakis flap method appears to be a safe and effective treatment option for sacrococcygeal pilonidal sinus, with an acceptable complication rate and no observed cases of recurrence.