Merck & Co. pays US$1.35 billion for LSD1 inhibitors

被引：3
|
作者：
Mullard, Asher
机构：
来源：
NATURE REVIEWS DRUG DISCOVERY | 2023年 / 22卷 / 01期
关键词：
D O I：
10.1038/d41573-022-00197-w
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：6 / 6
页数：1
相关论文
共 50 条
  • [1] Merck & Co. pays US$1.35 billion for LSD1 inhibitors
    Asher Mullard
    Nature Reviews Drug Discovery, 2023, 22 : 6 - 6
  • [2] Discovery of reversible LSD1 inhibitors
    Kanouni, Toufike
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [3] A comprehensive comparative study on LSD1 in different cancers and tumor specific LSD1 inhibitors
    Dong, Jianshu
    Pervaiz, Waqar
    Tayyab, Bilal
    Li, Die
    Kang, Lei
    Zhang, Huimin
    Gong, Huimin
    Ma, Xinli
    Li, Jian
    Agboyibor, Clement
    Bi, Yuefeng
    Liu, Hongmin
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 240
  • [4] Reversible Lysine Specific Demethylase 1 (LSD1) Inhibitors: A Promising Wrench to Impair LSD1
    Dai, Xing-Jie
    Liu, Ying
    Xue, Lei-Peng
    Xiong, Xiao-Peng
    Zhou, Ying
    Zheng, Yi-Chao
    Liu, Hong-Min
    JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (05) : 2466 - 2488
  • [5] Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors
    Gehling, Victor S.
    Mcgrath, John P.
    Duplessis, Martin
    Khanna, Avinash
    Brucelle, Francois
    Vaswani, Rishi G.
    Cote, Alexandre
    Stuckey, Jacob
    Watson, Venita
    Cummings, Richard T.
    Balasubramanian, Srividya
    Iyer, Priya
    Sawant, Priyanka
    Good, Andrew C.
    Albrecht, Brian K.
    Harmange, Jean-Christophe
    Audia, James E.
    Bellon, Steven F.
    Trojer, Patrick
    Levell, Julian R.
    ACS MEDICINAL CHEMISTRY LETTERS, 2020, 11 (06): : 1213 - 1220
  • [6] Dual inhibitors of LSD1 and spermine oxidase
    Holshouser, Steven
    Dunworth, Matthew
    Murray-Stewart, Tracy
    Peterson, Yuri K.
    Burger, Pieter
    Kirkpatrick, Joy
    Chen, Huan-Huan
    Casero, Robert A., Jr.
    Woster, Patrick M.
    MEDCHEMCOMM, 2019, 10 (05) : 778 - 790
  • [7] Discovery of potent reversible inhibitors of LSD1
    Chen, Young
    Kanouni, Toufike
    Severin, Christophe
    Xu, Jiangchun
    Del Rosario, Joselyn
    Shi, Lihong
    Lai, Chon
    Stafford, Jeffrey
    Veal, Jim
    Stansfield, Ryan
    Cho, Rob
    Yuen, Natalie
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258
  • [8] Merck & Co. buys TNF-superfamily-targeting antibody for $10.8 billion
    Mullard, Asher
    NATURE REVIEWS DRUG DISCOVERY, 2023, 22 (06) : 435 - 435
  • [9] Merck & Co. buys TNF-superfamily-targeting antibody for $10.8 billion
    Asher Mullard
    Nature Reviews Drug Discovery, 2023, 22 : 435 - 435
  • [10] Trends of LSD1 inhibitors in viral infections
    Zwergel, Clemens
    Stazi, Giulia
    Mai, Antonello
    Valente, Sergio
    FUTURE MEDICINAL CHEMISTRY, 2018, 10 (10) : 1133 - 1136
12345