Factors Associated With COVID-19 Non-vaccination in Adolescents Hospitalized Without COVID-19

被引：0

作者：

Sahni, Leila C. ^{[1
]}

Price, Ashley M. ^{[2
]}

Olson, Samantha M. ^{[2
]}

Newhams, Margaret M. ^{[3
]}

Pannaraj, Pia S. ^{[4
,5
,6
]}

Maddux, Aline B. ^{[7
,8
]}

Halasa, Natasha B. ^{[9
]}

Bline, Katherine E. ^{[10
]}

Cameron, Melissa A. ^{[11
]}

Schwartz, Stephanie P. ^{[12
]}

Walker, Tracie C. ^{[12
]}

Irby, Katherine ^{[13
]}

Chiotos, Kathleen ^{[14
]}

Nofziger, Ryan A. ^{[15
]}

Mack, Elizabeth H. ^{[16
]}

Smallcomb, Laura ^{[17
]}

Bradford, Tamara T. ^{[18
,19
]}

Kamidani, Satoshi ^{[20
,21
]}

Tarquinio, Keiko M. ^{[22
]}

Cvijanovich, Natalie Z. ^{[23
]}

Schuster, Jennifer E. ^{[24
]}

Bhumbra, Samina S. ^{[25
]}

Levy, Emily R. ^{[26
,27
]}

Hobbs, Charlotte, V ^{[28
]}

Cullimore, Melissa L. ^{[29
]}

Coates, Bria M. ^{[30
]}

Heidemann, Sabrina M. ^{[31
]}

Gertz, Shira J. ^{[32
]}

Kong, Michele ^{[33
]}

Flori, Heidi R. ^{[34
,35
]}

Staat, Mary A. ^{[36
]}

Zinter, Matt S. ^{[37
,38
]}

Hume, Janet R. ^{[39
]}

Chatani, Brandon M. ^{[40
]}

Gaspers, Mary G. ^{[41
]}

Maamari, Mia ^{[42
]}

Randolph, Adrienne G. ^{[3
,43
,44
]}

Patel, Manish M. ^{[2
]}

Boom, Julie A. ^{[1
]}

机构：

[1] Texas Childrens Hosp, Baylor Coll Med, Dept Pediat, Immunizat Project, Houston, TX 77030 USA

[2] Ctr Dis Control & Prevent, CDC COVID 19 Response Team, Atlanta, GA USA

[3] Boston Childrens Hosp, Dept Anesthesiol Crit Care & Pain Med, Boston, MA USA

[4] Childrens Hosp Los Angeles, Div Infect Dis, Los Angeles, CA 90027 USA

[5] Univ Southern Calif, Dept Pediat, Los Angeles, CA 90027 USA

[6] Univ Southern Calif, Dept Mol Microbiol & Immunol, Los Angeles, CA 90027 USA

[7] Univ Colorado, Sch Med, Dept Pediat, Sect Crit Care Med, Aurora, CO 80045 USA

[8] Childrens Hosp Colorado, Aurora, CO USA

[9] Vanderbilt Univ, Med Ctr, Dept Pediat, Div Pediat Infect Dis, Nashville, TN 37232 USA

[10] Nationwide Childrens Hosp Columbus, Div Pediat Crit Care Med, Columbus, OH USA

[11] UC San Diego Rady Childrens Hosp, Div Pediat Hosp Med, San Diego, CA USA

[12] Univ N Carolina, Dept Pediat, Childrens Hosp, Chapel Hill, NC 27514 USA

[13] Arkansas Childrens Hosp, Dept Pediat, Sect Pediat Crit Care, Little Rock, AR 72202 USA

[14] Childrens Hosp Philadelphia, Div Crit Care Med, Dept Anesthesiol & Crit Care, Philadelphia, PA 19104 USA

[15] Akron Childrens Hosp, Div Crit Care Med, Dept Pediat, Akron, OH 44308 USA

[16] Med Univ South Carolina, Div Pediat Crit Care Med, Charleston, SC 29425 USA

[17] Med Univ South Carolina, Dept Pediat, Charleston, SC 29425 USA

[18] Louisiana State Univ, Hlth Sci Ctr, Dept Pediat, Div Cardiol, New Orleans, LA 70118 USA

[19] Childrens Hosp New Orleans, New Orleans, LA 70118 USA

[20] Childrens Healthcare Atlanta, Ctr Childhood Infect & Vaccines, Atlanta, GA USA

[21] Emory Univ, Sch Med, Dept Pediat, Atlanta, GA 30322 USA

[22] Emory Univ, Sch Med, Dept Pediat, Div Crit Care Med,Childrens Healthcare Atlanta, Atlanta, GA 30322 USA

[23] UCSF Benioff Childrens Hosp Oakland, Div Crit Care Med, Oakland, CA USA

[24] Childrens Mercy Kansas City, Div Pediat Infect Dis, Dept Pediat, Kansas City, MO USA

[25] Indiana Univ Sch Med, Ryan White Ctr Pediat Infect Dis & Global Hlth, Dept Pediat, Indianapolis, IN 46202 USA

[26] Mayo Clin, Div Pediat Infect Dis, Dept Pediat & Adolescent Med, Rochester, MN USA

[27] Mayo Clin, Div Pediat Crit Care Med, Dept Pediat & Adolescent Med, Rochester, MN USA

[28] Univ Mississippi Med Ctr, Dept Pediat, Dept Microbiol, Div Infect Dis, Jackson, MS USA

[29] Childrens Hosp & Med Ctr, Dept Pediat, Div Pediat Crit Care, Omaha, NE 68114 USA

[30] Northwestern Univ, Ann & Robert H Lurie Childrens Hosp Chicago, Dept Pediat, Div Crit Care Med,Feinberg Sch Med, Chicago, IL 60611 USA

[31] Cent Michigan Univ, Childrens Hosp MI, Div Pediat Crit Care Med, Detroit, MI 48201 USA

[32] Cooperman Barnabas Med Ctr, Dept Pediat, Div Pediat Crit Care, Livingston, NJ USA

[33] Univ Alabama Birmingham, Dept Pediat, Div Pediat Crit Care Med, Birmingham, AL USA

[34] Mott Childrens Hosp, Dept Pediat, Div Pediat Crit Care Med, Ann Arbor, MI USA

[35] Univ Michigan, Ann Arbor, MI 48109 USA

[36] Univ Cincinnati, Cincinnati Childrens Hosp Med Ctr, Dept Pediat, Coll Med, Cincinnati, OH USA

[37] Univ Calif San Francisco, Dept Pediat, Div Crit Care Med, San Francisco, CA USA

[38] Univ Calif San Francisco, Dept Pediat, Div Allergy Immunol & Bone Marrow Transplant, San Francisco, CA USA

[39] Univ Minnesota, Div Pediat Crit Care, Masonic Childrens Hosp, Minneapolis, MN USA

[40] UHlth Holtz Childrens Hosp, Dept Pediat, Div Pediat Infect Dis, Miami, FL USA

[41] Univ Arizona, Diamond Childrens Banner Childrens Med Ctr, Tucson, AZ USA

[42] Univ Texas Southwestern, Childrens Med Ctr Dallas, Dept Pediat, Div Crit Care Med, Dallas, TX USA

[43] Harvard Med Sch, Dept Anaesthesia, Boston, MA 02115 USA

[44] Harvard Med Sch, Dept Pediat, Boston, MA 02115 USA

来源：

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2023年 / 12卷 / 01期

关键词：

adolescent; COVID-19; vaccine; risk factors; UNITED-STATES; CHILDREN; US;

D O I：

10.1093/jpids/piac113

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Background Pfizer-BioNTech COVID-19 vaccine received emergency use authorization for persons >= 16 years in December 2020 and for adolescents 12-15 years in May 2021. Despite the clear benefits and favorable safety profile, vaccine uptake in adolescents has been suboptimal. We sought to assess factors associated with COVID-19 non-vaccination in adolescents 12-18 years of age. Methods Between June 1, 2021 and April 29, 2022, we assessed factors associated with COVID-19 non-vaccination in hospitalized adolescents ages 12-18 years enrolled in the Overcoming COVID-19 vaccine effectiveness network. Demographic characteristics and clinical information were captured through parent interviews and/or electronic medical record abstraction; COVID-19 vaccination was assessed through documented sources. We assessed associations between receipt of the COVID-19 vaccine and demographic and clinical factors using univariate and multivariable logistic regression and estimated adjusted odds ratios (aOR) for each factor associated with non-vaccination. Results Among 1665 hospitalized adolescents without COVID-19, 56% were unvaccinated. Unvaccinated adolescents were younger (median age 15.1 years vs. 15.4 years, p < .01) and resided in areas with higher social vulnerability index (SVI) scores (median 0.6 vs 0.5, p < .001) than vaccinated adolescents. Residence in the Midwest [aOR 2.60 (95% CI: 1.80, 3.79)] or South [aOR 2.49 (95% CI: 1.77, 3.54)] US census regions, rarely or never receiving influenza vaccine [aOR 5.31 (95% CI: 3.81, 7.47)], and rarely or never taking precautions against COVID-19 [aOR 3.17 (95% CI: 1.94, 5.31)] were associated with non-vaccination against COVID-19. Conclusions Efforts to increase COVID-19 vaccination of adolescents should focus on persons with geographic, socioeconomic, and medical risk factors associated with non-vaccination.

引用

页码：29 / 35

页数：7

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