A Comprehensive Review of Herbal Medicines for the Treatment of Alzheimer's Disease

被引:1
|
作者
Shadab, Sumbul [1 ]
Rao, G. S. N. Koteswara [1 ,2 ]
Paliwal, Deepika [1 ]
Yadav, Devdhar [1 ]
Alam, Aftab [1 ]
Singh, Amit [1 ]
Sultana, Md Jaha [3 ]
机构
[1] Galgotias Univ, Sch Med & Allied Sci, Dept Pharm, Greater Noida, Uttar Pradesh, India
[2] SVKMS NMIMS, Shobhaben Pratapbhai Patel Sch Pharm & Technol Man, VL Mehta Rd,Vile Parle W, Mumbai 400056, India
[3] Koneru Lakshmaiah Educ Fdn, K L Coll Pharm, Vaddeswaram, Andhra Prades, India
关键词
Alzheimer's disease; cerebral blood flow; memory; medicinal plants; active component; seniles plaque; MODERATE ALZHEIMERS-DISEASE; DERIVATIVE 2-(4 BENZYLOXYPHENYL)-3-HYDROXY-CHROMEN-4-ONE; CHOLINESTERASE INHIBITORY-ACTIVITY; SALVIA-OFFICINALIS L; CORIANDRUM-SATIVUM L; KOREAN RED GINSENG; GINKGO-BILOBA; DOUBLE-BLIND; MOUSE MODEL; COGNITIVE PERFORMANCE;
D O I
10.2174/2215083810666230608151821
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
The choices of treatment for Alzheimer's are based on NMDA-receptor antagonists and cholinesterase inhibitors, although their efficacy as a therapy is still up for debate. BPSD (Behavioural and Psychological Symptoms of Dementia) have been treated using herbal medicine products, with varying degrees of success. This manuscript sets out to answer the question, "Can herbs be effective in the treatment of cognitive impairments in patients?" by examining evidences from controlled research. The process by which Alzheimer's disease develops remains a mystery, and the present Alzheimer's treatment strategy, which consists of administering a single medicine to treat a single target, appears to be clinically ineffective. AD treatment will require a combination of approaches that target many signs and causes of the disease. The results of currently available licensed therapies for AD are often disappointing, and alternative medicine, especially herbal therapy, may play a role. Over 80% of the world's population, particularly in developing nation, gets their main health care from herbal medicines. They have persisted through the years due to their low risk, high reward, widespread acceptance across cultures, and absence of detrimental side effects. In some cases, herbal remedies have proven to be more effective than conventional medical treatments. They are assumed to be natural unless proven otherwise by the presence of unnatural additives. The absence of adverse reactions is a major advantage of herbal treatment. In addition, they provide ongoing advantages to health. Salvia officinalis, Ginkgo biloba, Melissa officinalis, Panax ginseng, Coriandrum sativum, Curcuma longa, Ashwagandha, Uncaria Tomentosa, Crocus Sativus and Allium Sativum are all studied for their potential effects on Alzheimer's disease.
引用
收藏
页码:98 / 116
页数:19
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