On-treatment clinical remission with tezepelumab in patients with severe, uncontrolled asthma in the phase 3 DESTINATION study

被引：2

作者：

Wechsler, Michael E. ^{[1
]}

Brusselle, Guy ^{[2
]}

Virchow, J. Christian ^{[3
,4
]}

Heaney, Liam G. ^{[5
]}

Hunter, Gillian ^{[6
]}

Ponnarambil, Sandhia ^{[7
]}

Martin, Neil ^{[8
,9
]}

Llanos, Jean-Pierre ^{[10
]}

Porsbjerg, Celeste ^{[11
,12
]}

Brightling, Christopher E. ^{[13
]}

机构：

[1] Natl Jewish Hlth, Denver, CO USA

[2] Ghent Univ Hosp, Dept Resp Med, Ghent, Belgium

[3] Univ Rostock, Dept Pneumol, Rostock, Germany

[4] Univ Rostock, Dept Intens Care Med, Rostock, Germany

[5] Queens Univ Belfast, Wellcome Wolfson Inst Expt Med, Sch Med Dent & Biomed Sci, Belfast, Antrim, North Ireland

[6] AstraZeneca, Late Stage Dev Resp & Immunol, Biometr, BioPharmaceut R&D, Cambridge, England

[7] AstraZeneca, Late Stage Dev Resp & Immunol, BioPharmaceut R&D, Cambridge, England

[8] AstraZeneca, Resp & Immunol, Biopharmaceut Med, Cambridge, England

[9] Univ Leicester, Leicester, Leics, England

[10] Global Med Affairs, Thousand Oaks, CA USA

[11] Univ Copenhagen, Dept Resp Med, Bispebjerg Hosp, Copenhagen, Denmark

[12] Univ Copenhagen, Inst Clin Med, Copenhagen, Denmark

[13] Univ Leicester, Inst Lung Hlth, Natl Inst Hlth & Care Res, Leicester Biomed Res Ctr, Leicester, Leics, England

来源：

EUROPEAN RESPIRATORY JOURNAL | 2023年 / 62卷

关键词：

Asthma; -; management;

D O I：

10.1183/13993003.congress-2023.PA4722

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

引用

页数：3

共 50 条

[1] ON-TREATMENT CLINICAL REMISSION WITH TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA IN THE PHASE 3 DESTINATION STUDY
Wechsler, M. E.
Brusselle, G.
Virchow, J. C.
Heaney, L. G.
Hunter, G.
Ponnarambil, S.
Martin, N.
Llanos, J-P
Porsbjerg, C.
Brightling, C. E.
THORAX, 2023, 78 (SUPPL_4) : A272 - A273
[2] On-treatment clinical remission with tezepelumab among patients with severe, uncontrolled asthma in the phase 3 NAVIGATOR study
Castro, M.
Ambrose, C. S.
Colice, G.
Roseti, S. L.
Kmita, K.
Cook, B.
Martin, N.
Llanos-Ackert, J.
Menzies-Gow, A.
EUROPEAN RESPIRATORY JOURNAL, 2022, 60
[3] Clinical response and on-treatment clinical remission with tezepelumab in a broad population of patients with severe, uncontrolled asthma: results over 2 years from the NAVIGATOR and DESTINATION studies
Wechsler, Michael E.
Brusselle, Guy
Virchow, J. Christian
Bourdin, Arnaud
Kostikas, Konstantinos
Llanos, Jean-Pierre
Roseti, Stephanie L.
Ambrose, Christopher S.
Hunter, Gillian
Jackson, David J.
Castro, Mario
Lugogo, Njira
Pavord, Ian D.
Martin, Neil
Brightling, Christopher E.
EUROPEAN RESPIRATORY JOURNAL, 2024, 64 (06)
[4] Clinical Responses to Treatment with Tezepelumab Among Patients with Severe, Uncontrolled Asthma in the Phase 3 NAVIGATOR Study
Lugogo, N. L.
Ambrose, C. S.
Colice, G.
Kmita, K.
Cook, B.
Ponnarambil, S.
Ackert, J. Llanos
Menzies-Gow, A.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2022, 205
[5] Tezepelumab in the Treatment of Uncontrolled Severe Asthma
Feist, Jacqueline
Lipari, Melissa
Kale-Pradhan, Pramodini
ANNALS OF PHARMACOTHERAPY, 2023, 57 (01) : 62 - 70
[6] Effect of Tezepelumab on Lung Function in Patients With Severe, Uncontrolled Asthma in the Phase 3 NAVIGATOR Study
Menzies-Gow, Andrew
Ambrose, Christopher S.
Colice, Gene
Hunter, Gillian
Cook, Bill
Molfino, Nestor A.
Llanos, Jean-Pierre
Israel, Elliot
ADVANCES IN THERAPY, 2023, 40 (11) : 4957 - 4971
[7] EFFECT OF TEZEPELUMAB ON LUNG FUNCTION IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA IN THE PHASE 3 NAVIGATOR STUDY
Israel, Elliot
Menzies-Gow, Andrew
Colice, Gene
Ambrose, Christopher
Hunter, Gillian
Cook, William
Molfino, Nestor
Llanos-Ackert, Jean-Pierre
CHEST, 2021, 160 (04) : 41A - 43A
[8] Effect of Tezepelumab on Lung Function in Patients With Severe, Uncontrolled Asthma in the Phase 3 NAVIGATOR Study
Andrew Menzies-Gow
Christopher S. Ambrose
Gene Colice
Gillian Hunter
Bill Cook
Nestor A. Molfino
Jean-Pierre Llanos
Elliot Israel
Advances in Therapy, 2023, 40 : 4957 - 4971
[9] Tezepelumab Treatment Reduced Asthma Symptomatic Days in Adults and Adolescents with Severe, Uncontrolled Asthma in the Phase 3 NAVIGATOR Study
Carr, Warner
Jain, Neal
Ambrose, Chris
Clarke, Nicole
Martin, Neil
Kmita, Kamil
Desai, Pooja
Llanos-Ackert, Jean-Pierre
Ponnarambil, Sandhia
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2022, 149 (02) : AB16 - AB16
[10] Efficacy of Tezepelumab in Patients With Severe, Uncontrolled Asthma by Sex: Results From the Phase 3 Navigator Study
Kraft, M.
Chupp, G. L.
Reeh, K.
Lindsley, A. W.
Cook, B.
Hunter, G.
Ambrose, C. S.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2023, 207

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