Organic Electrochemical Transistors for Biomarker Detections

The improvement of living standards and the advancement of medical technology have led to an increased focus on health among individuals. Detections of biomarkers are feasible approaches to obtaining information about health status, disease progression, and response to treatment of an individual. In recent years, organic electrochemical transistors (OECTs) have demonstrated high electrical performances and effectiveness in detecting various types of biomarkers. This review provides an overview of the working principles of OECTs and their performance in detecting multiple types of biomarkers, with a focus on the recent advances and representative applications of OECTs in wearable and implantable biomarker detections, and provides a perspective for the future development of OECT-based biomarker sensors. This review provides a comprehensive overview of biomarker sensors based on organic electrochemical transistors (OECTs) and their associated detection methodologies. OECTs demonstrate the ability to detect a diverse range of biomarkers, exhibiting advantages including high sensitivity, biocompatibility, and flexibility. The applications of OECT-based biomarker sensors in wearable, implantable, and portable electronics are discussed, elucidating their practical implications.image