breast conserving therapy;
elderly;
immediate oncoplastic reduction;
SURGERY;
OUTCOMES;
OLDER;
D O I:
10.1002/jso.27635
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Background/Objectives: Oncoplastic reconstruction (IOR) performed in conjunction with breast conserving therapy (BCT) has been found to improve psychosocial well-being, reduce hospitalization time, and reduce cost burden. Few studies have looked at the safety profile, complication rates, and overall outcomes in patients ages 65 years and older undergoing IOR versus BCT alone. Methods: A retrospective, cross-sectional, single-institution medical record review was conducted of women diagnosed with breast cancer age 65 years or older who received IOR or BCT alone. Demographics, clinical data, and major and minor complication profiles were compared between cohorts. Results: A total of 310 patients were included. Of these, 126 received IOR, while 184 received BCT alone. Age >85 was found to have a significantly higher risk for any complication and was an independent predictor for experiencing any complication (OR: 8.5, p = 0.015; OR: 1.06, p = 0.029). Major complication rates were significantly higher in the BCT cohort (16.9% vs. 7.9%, p = 0.023). Conclusion: IOR in the elderly is a safe option and was not found to be a predictor of experiencing higher complications. Patients who are 85 years and older had a higher risk of complications, and future studies may explore risk-benefit in that particular cohort of patients in which BCT is planned.
机构:
Sun Yat Sen Univ, Canc Ctr, Guangzhou, Guangdong, Peoples R China
State Key Lab Oncol South China, Guangzhou, Guangdong, Peoples R China
Collaborat Innovat Ctr Canc Med, Guangzhou, Guangdong, Peoples R ChinaSun Yat Sen Univ, Canc Ctr, Guangzhou, Guangdong, Peoples R China
Chen, Jun-Ying
Huang, Yi-Jie
论文数: 0引用数: 0
h-index: 0
机构:
Guangdong Acad Med Sci, Guangdong Gen Hosp, Dept Gen Surg, Guangzhou, Guangdong, Peoples R ChinaSun Yat Sen Univ, Canc Ctr, Guangzhou, Guangdong, Peoples R China
Huang, Yi-Jie
Zhang, Liu-Lu
论文数: 0引用数: 0
h-index: 0
机构:
Guangdong Acad Med Sci, Guangdong Gen Hosp, Dept Breast Canc, Guangzhou, Guangdong, Peoples R ChinaSun Yat Sen Univ, Canc Ctr, Guangzhou, Guangdong, Peoples R China
Zhang, Liu-Lu
Yang, Ci-Qiu
论文数: 0引用数: 0
h-index: 0
机构:
Guangdong Acad Med Sci, Guangdong Gen Hosp, Dept Breast Canc, Guangzhou, Guangdong, Peoples R ChinaSun Yat Sen Univ, Canc Ctr, Guangzhou, Guangdong, Peoples R China
Yang, Ci-Qiu
Wang, Kun
论文数: 0引用数: 0
h-index: 0
机构:
Guangdong Acad Med Sci, Guangdong Gen Hosp, Dept Breast Canc, Guangzhou, Guangdong, Peoples R ChinaSun Yat Sen Univ, Canc Ctr, Guangzhou, Guangdong, Peoples R China
机构:
Emory Univ, Div Plast & Reconstruct Surg, 3200 Downwood Circle,Suite 640-4, Atlanta, GA 30327 USAEmory Univ, Div Plast & Reconstruct Surg, 3200 Downwood Circle,Suite 640-4, Atlanta, GA 30327 USA
Thompson, Peter W.
Chatterjee, Abhishek
论文数: 0引用数: 0
h-index: 0
机构:
Tufts Sch Med, Tufts Med Ctr, Div Surg Oncol & Plast Surg, Boston, MA USAEmory Univ, Div Plast & Reconstruct Surg, 3200 Downwood Circle,Suite 640-4, Atlanta, GA 30327 USA
Chatterjee, Abhishek
Losken, Albert
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h-index: 0
机构:
Emory Univ, Div Plast & Reconstruct Surg, 3200 Downwood Circle,Suite 640-4, Atlanta, GA 30327 USAEmory Univ, Div Plast & Reconstruct Surg, 3200 Downwood Circle,Suite 640-4, Atlanta, GA 30327 USA
机构:
Osaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, JapanOsaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, Japan
Hashimoto, Y.
Ishitobi, M.
论文数: 0引用数: 0
h-index: 0
机构:
Osaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, JapanOsaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, Japan
Ishitobi, M.
Okuno, J.
论文数: 0引用数: 0
h-index: 0
机构:
Osaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, Japan
Osaka Univ, Dept Breast & Endocrine Surg, Osaka, JapanOsaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, Japan
Okuno, J.
Tashima, H.
论文数: 0引用数: 0
h-index: 0
机构:
Osaka Int Canc Inst, Dept Plast & Reconstruct Surg, Osaka, JapanOsaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, Japan
Tashima, H.
Kurita, T.
论文数: 0引用数: 0
h-index: 0
机构:
Osaka Int Canc Inst, Dept Plast & Reconstruct Surg, Osaka, JapanOsaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, Japan
Kurita, T.
Tokui, R.
论文数: 0引用数: 0
h-index: 0
机构:
Osaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, JapanOsaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, Japan
Tokui, R.
Ota, C.
论文数: 0引用数: 0
h-index: 0
机构:
Osaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, JapanOsaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, Japan
Ota, C.
Kittaka, N.
论文数: 0引用数: 0
h-index: 0
机构:
Osaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, JapanOsaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, Japan
Kittaka, N.
Nakayama, T.
论文数: 0引用数: 0
h-index: 0
机构:
Osaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, JapanOsaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, Japan
Nakayama, T.
Tamaki, Y.
论文数: 0引用数: 0
h-index: 0
机构:
Osaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, JapanOsaka Int Canc Inst, Dept Breast & Endocrine Surg, Osaka, Japan
机构:
Huazhong Univ Sci & Technol, Hubei Canc Hosp, Tongji Med Coll, Hubei Prov Clin Res Ctr Breast Canc,Dept Breast Su, 116 Zhuo Daoquan South Rd, Wuhan 430079, Hubei, Peoples R ChinaHuazhong Univ Sci & Technol, Hubei Canc Hosp, Tongji Med Coll, Hubei Prov Clin Res Ctr Breast Canc,Dept Breast Su, 116 Zhuo Daoquan South Rd, Wuhan 430079, Hubei, Peoples R China
Tian, Rui
Zheng, Yu
论文数: 0引用数: 0
h-index: 0
机构:
Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Breast & Thyroid Surg, Wuhan, Peoples R ChinaHuazhong Univ Sci & Technol, Hubei Canc Hosp, Tongji Med Coll, Hubei Prov Clin Res Ctr Breast Canc,Dept Breast Su, 116 Zhuo Daoquan South Rd, Wuhan 430079, Hubei, Peoples R China
Zheng, Yu
Liu, Ruikang
论文数: 0引用数: 0
h-index: 0
机构:
Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Rehabil, Wuhan, Peoples R ChinaHuazhong Univ Sci & Technol, Hubei Canc Hosp, Tongji Med Coll, Hubei Prov Clin Res Ctr Breast Canc,Dept Breast Su, 116 Zhuo Daoquan South Rd, Wuhan 430079, Hubei, Peoples R China
Liu, Ruikang
Jiang, Chen
论文数: 0引用数: 0
h-index: 0
机构:
Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Cardiovasc Surg, 1277 Jiefang Ave, Wuhan 430022, Hubei, Peoples R ChinaHuazhong Univ Sci & Technol, Hubei Canc Hosp, Tongji Med Coll, Hubei Prov Clin Res Ctr Breast Canc,Dept Breast Su, 116 Zhuo Daoquan South Rd, Wuhan 430079, Hubei, Peoples R China
Jiang, Chen
Zheng, Hongmei
论文数: 0引用数: 0
h-index: 0
机构:
Huazhong Univ Sci & Technol, Hubei Canc Hosp, Tongji Med Coll, Hubei Prov Clin Res Ctr Breast Canc,Dept Breast Su, 116 Zhuo Daoquan South Rd, Wuhan 430079, Hubei, Peoples R ChinaHuazhong Univ Sci & Technol, Hubei Canc Hosp, Tongji Med Coll, Hubei Prov Clin Res Ctr Breast Canc,Dept Breast Su, 116 Zhuo Daoquan South Rd, Wuhan 430079, Hubei, Peoples R China