Antisense oligonucleotides targeting microRNA binding sites in the GRN mRNA increase progranulin translation: potential therapeutic strategy for frontotemporal dementia

被引：0
|
作者：
Jones, Spencer [1 ]
Aggarwal, Geetika [1 ]
Benchaar, Yousri [2 ]
Belanger, Jasmine [2 ]
Sevigny, Myriam [2 ]
Smith, Denise [1 ]
Niehoff, Michael [1 ]
de Vera, Ian Mitchelle
Petkau, Terri [3 ]
Leavitt, Blair [3 ]
Ling, Karen [4 ]
Jafar-Nejad, Paymaan [4 ]
Rigo, Frank [1 ,4 ]
Morley, John [1 ]
Nguyen, Andrew [1 ]
机构：
[1] St Louis Univ, St Louis, MO 63103 USA
[2] Univ Laval, Quebec City, PQ, Canada
[3] Univ British Columbia, Vancouver, BC, Canada
[4] Ionis Pharmaceut, Carlsbad, CA USA
来源：
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS | 2023年 / 385卷
关键词：
D O I：
10.1124/jpet.122.246730
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
167
引用
收藏
页数：1
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