Foregoing elective neck dissection for elderly patients with oral cavity squamous cell carcinoma

被引:1
|
作者
Tsur, Nir [1 ,2 ,4 ]
Yosefof, Eyal [1 ,2 ]
Dudkiewicz, Dean [1 ,2 ]
Edri, Nofar [1 ,2 ]
Stern, Sagit [3 ]
Shpitzer, Thomas [1 ,2 ]
Mizrachi, Aviram [1 ,2 ]
Najjar, Esmat [1 ,2 ]
机构
[1] Rabin Med Ctr, Dept Otorhinolaryngol Head & Neck Surg, Petah Tiqwa, Israel
[2] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel
[3] Hadassah Univ Hosp, Otolaryngol Head & Neck Surg, Jerusalem, Israel
[4] Rabin Med Ctr, Dept Otorhinolaryngol Head & Neck Surg, Beilinson Campus, IL-49100 Petah Tiqwa, Israel
关键词
aged; carcinoma; elective neck dissection; humans; mouth neoplasms; old age; retrospective; squamous cell; squamous cell carcinoma of head and neck; survival rate; ACUTE MYELOID-LEUKEMIA; LYMPH-NODE METASTASIS; QUALITY-OF-LIFE; BIOLOGICAL AGE; THERAPEUTIC NECK; CANCER; TONGUE; HEAD; COMPLICATIONS; EPIDEMIOLOGY;
D O I
10.1111/ans.18711
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objective: Elective neck dissection (END) improves outcomes among clinically node-negative patients with oral cavity squamous cell carcinoma (OCSCC). However, END is of questionable value, considering the potentially higher comorbidities and operative risks in elderly patients.Methods: A retrospective review of all patients older than 65 years of age who were treated for OCSCC at a tertiary care centre between 2005 and 2020 was conducted.Results: Fifty-three patients underwent primary tumour resection alone, and 71 had simultaneous END. Most primary tumours were located on the mobile tongue. The patients who did not undergo END had a higher mean age (81.2 vs. 75.1 years, P < 0.00001), significantly shorter surgeries, and shorter hospitalizations. Occult cervical metastases were found in 24% of the patients who underwent END. The two groups showed no significant differences in overall survival or recurrence rates. Similar results were shown in a subpopulation analysis of patients older than 75 years.Conclusion: Foregoing END in elderly patients with no clinical evidence of neck metastases di: d not result in lower survival rates or higher recurrence rates.
引用
收藏
页码:128 / 139
页数:12
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