Does dietary intake of caffeine have an effect on transient global amnesia?

AimAmnesia is a cognitive disorder that may lead to memory loss. Caffeine is a psychoactive substance which have an effect on memory and cognitive functions. This study aimed to assess the association of transient global amnesia (TGA) with dietary intake of caffeine.MethodsThis cross-sectional study was conducted on the Sabzevar Persian cohort data of 258 patients with TGA and 520 healthy individuals in Sabzevar, Iran. The Nutritional data were gathered in face-to-face interviews using a valid Food Frequency Questionnaire. Different models of logistic regression were used to determine the association between TGA and dietary caffeine intake after adjusting the confounders including age, sex, education, job, marital status, physical activity, BMI, and calorie intake.ResultsThere was no significant difference in terms of dietary calorie intake of (2279.5 +/- 757.9 vs. 2365.5 +/- 799.5, p = 0.19), protein (70.79 +/- 25.27 vs. 72.94 +/- 24.83, p = 0.31), fat (59.97 +/- 23.79 vs. 60.13 +/- 26.38, p = 0.93), carbohydrate (376 +/- 134 vs. 393.1 +/- 137.8, p = 0.14), and caffeine (196.4 +/- 127.9 vs. 186.3 +/- 128.5, p = 0.36) between the groups. No significant association was found between TGA and dietary intake of caffeine (OR: 0.99, 95% CI: 0.99-1.01, p = 0.36). The results did not change after adjusting the confounders.ConclusionsNo significant association was found between TGA and dietary intake of caffeine. Further prospective studies are required to confirm this finding. Our study examined the link between transient global amnesia (TGA) and dietary caffeine intake in a large group of participants and found no significant association between TGA and caffeine.image