First Reported Case of Successful Conception and Delivery During Stage IV Breast Cancer Treatment: A Case Report and Literature Review

被引：0

作者：

Al-shamsi, Humaid O. ^{[1
,2
,3
]}

Abdelwahed, Nadia ^{[4
]}

Singh, Mandeep ^{[5
]}

Abyad, Amin M. ^{[4
]}

Elsabae, Shimaa ^{[6
]}

Abdelgawad, Tamer ^{[6
]}

Iqbal, Faryal ^{[7
]}

Ibrahim, Nuhad ^{[8
]}

机构：

[1] Burjeel Med City, Dept Oncol, Burjeel Holdings Oncol Serv, Abu Dhabi, U Arab Emirates

[2] Gulf Med Univ, Coll Med, Dept Biomed Sci, Ajman, U Arab Emirates

[3] Emirates Med Assoc, Div Gastroenterol, Dubai, U Arab Emirates

[4] Burjeel Med City, Dept Med, Abu Dhabi, U Arab Emirates

[5] Burjeel Med City, Kypros Nicolaides Fetal Med & Therapy Ctr, Dept Fetal Med & Therapy, Abu Dhabi, U Arab Emirates

[6] Burjeel Med City, Dept Radiol, Abu Dhabi, U Arab Emirates

[7] Burjeel Med City, Dept Res & Dev, Abu Dhabi, U Arab Emirates

[8] Univ Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Houston, TX USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 10期

关键词：

pertuzumab; trastuzumab; malignancy; her2; pregnancy; breast cancer; PREGNANCY; TRASTUZUMAB; THERAPY;

D O I：

10.7759/cureus.47201

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We herein report a case involving a woman with metastatic human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC) who became pregnant while undergoing active anticancer therapy with Trastuzumab-Pertuzumab for her advanced BC disease at our institution. To our knowledge, this is the first reported case of pregnancy and successful delivery in a stage IV BC patient during anticancer therapy. A multidisciplinary approach for such a complex case is a must to evaluate the mother's medical condition by an experienced oncology team along with a maternal-fetal team, with support from a psychiatric and psychological evaluation for the mother. The use of effective contraception during anticancer therapy is essential to avoid such a scenario.

引用

页数：10

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