Preparation and Permeation Properties of a pH-Responsive Polyacrylic Acid Coated Porous Alumina Membrane

A pH-responsive membrane is expected to be used for applications such as drug delivery, controlling chemical release, bioprocessing, and water treatment. Polyacrylic acid (PAA) is a pH-responsive polymer that swells at high pH. A tubular alpha-alumina porous support was coated with PAA by grafting to introduce appropriate functional groups, followed by polymerization with acrylic acid. The permeances of acetic acid, lactic acid, phenol, and caffeine were evaluated by circulating water inside the membrane, measuring the concentration of species that permeated into the water, and analyzing the results with the permeation model. The permeance of all species decreased with increasing pH, and that of phenol was the largest among these species. At high pH, the PAA carboxy group in the membrane dissociated into carboxy ions and protons, causing the swelling of PAA due to electrical repulsion between the negative charges of the PAA chain, which decreased the pore size of the membrane and suppressed permeation. Furthermore, the electrical repulsion between negatively charged species and the PAA membrane also suppressed the permeation. The results of this study demonstrated that the PAA-coated alpha-alumina porous support functioned as a pH-responsive membrane.