Metabonomic analysis of tumor microenvironments: a mini-review

被引:2
|
作者
Zeng, Zeng [1 ,2 ]
Chen, Cong-Xian [1 ]
机构
[1] Hangzhou Med Coll, Zhejiang Prov Peoples Hosp, Affiliated Peoples Hosp, Canc Ctr,Dept Ultrasound Med, Hangzhou, Zhejiang, Peoples R China
[2] Zhejiang Univ, Sch Med, Hangzhou, Peoples R China
来源
FRONTIERS IN ONCOLOGY | 2023年 / 13卷
关键词
metabonomic; metabolomic; metabolism; tumor; drug resistance; COLORECTAL-CANCER; METABOLISM; METABOLOMICS; METASTASIS; PROTEOMICS; RELEVANCE;
D O I
10.3389/fonc.2023.1164266
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Metabolomic analysis is a vital part of studying cancer progression. Metabonomic crosstalk, such as nutrient availability, physicochemical transformation, and intercellular interactions can affect tumor metabolism. Many original studies have demonstrated that metabolomics is important in some aspects of tumor metabolism. In this mini-review, we summarize the definition of metabolomics and how it can help change a tumor microenvironment, especially in pathways of three metabonomic tumors. Just as non-invasive biofluids have been identified as early biomarkers of tumor development, metabolomics can also predict differences in tumor drug response, drug resistance, and efficacy. Therefore, metabolomics is important for tumor metabolism and how it can affect oncology drugs in cancer therapy.
引用
收藏
页数:6
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