Whole-genome resource sequences of 57 indigenous Ethiopian goats

被引:5
|
作者
Belay, Shumuye [1 ,2 ,3 ]
Belay, Gurja [2 ]
Nigussie, Helen [2 ]
Jian-Lin, Han [4 ]
Tijjani, Abdulfatai [3 ]
Ahbara, Abulgasim M. [5 ,6 ]
Tarekegn, Getinet M. [5 ,7 ]
Woldekiros, Helina S. [8 ]
Mor, Siobhan [3 ,9 ]
Dobney, Keith [10 ,11 ]
Lebrasseur, Ophelie [10 ]
Hanotte, Olivier [3 ,12 ]
Mwacharo, Joram M. [5 ,13 ]
机构
[1] Tigray Agr Res Inst, Mekelle, Tigray, Ethiopia
[2] Addis Ababa Univ, Dept Microbial Cellular & Mol Biol, Addis Ababa, Ethiopia
[3] Int Livestock Res Inst ILRI, Live Gene Program, Addis Ababa, Ethiopia
[4] ILRI CAAS Joint Lab Livestock & Forage Genet Resou, Beijing, Peoples R China
[5] Scotlands Rural Coll SRUC, Anim & Vet Sci, Roslin Inst Bldg, Edinburgh, Midlothian, Scotland
[6] Misurata Univ, Dept Zool, Misurata, Libya
[7] Addis Ababa Univ, Inst Biotechnol, Addis Ababa, Ethiopia
[8] Washington Univ St Louis, Dept Anthropol, St Louis, MO USA
[9] Univ Liverpool, Inst Infect Vet & Ecol Sci, Liverpool, England
[10] Univ Liverpool, Dept Archaeol Class & Egyptol, Liverpool, England
[11] Univ Sydney, Sch Philosoph & Hist Inquiry, Sydney, Australia
[12] Univ Nottingham, Sch Life Sci, Nottingham, England
[13] Int Ctr Agr Res Dry Areas ICARDA, Small Ruminant Genom, Addis Ababa, Ethiopia
基金
英国科研创新办公室; 英国生物技术与生命科学研究理事会;
关键词
GENETIC DIVERSITY; CAPRA-HIRCUS; MICROSATELLITE; BREEDS;
D O I
10.1038/s41597-024-02973-2
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Domestic goats are distributed worldwide, with approximately 35% of the one billion world goat population occurring in Africa. Ethiopia has 52.5 million goats, similar to 99.9% of which are considered indigenous landraces deriving from animals introduced to the Horn of Africa in the distant past by nomadic herders. They have continued to be managed by smallholder farmers and semi-mobile pastoralists throughout the region. We report here 57 goat genomes from 12 Ethiopian goat populations sampled from different agro-climates. The data were generated through sequencing DNA samples on the Illumina NovaSeq 6000 platform at a mean depth of 9.71x and 150 bp pair-end reads. In total, similar to 2 terabytes of raw data were generated, and 99.8% of the clean reads mapped successfully against the goat reference genome assembly at a coverage of 99.6%. About 24.76 million SNPs were generated. These SNPs can be used to study the population structure and genome dynamics of goats at the country, regional, and global levels to shed light on the species' evolutionary trajectory.
引用
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页数:10
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