Diastereo- and π-Facially Selective Hetero-Diels Alder Cycloaddition Reactions of 3-Butadienyl-2-Azetidinones with Diazo-Dienophiles

被引：0
|
作者：
Mann, Maninderjeet Kaur [1 ]
Sharma, Rashmi [1 ]
Chawla, Pooja [2 ]
Kumar, Rupesh [1 ]
Bhargava, Gaurav [1 ]
机构：
[1] IK Gujral Punjab Tech Univ, Dept Chem Sci, Kapurthala, Punjab, India
[2] ISF Coll Pharm, Dept Pharmaceut Chem, Moga, Punjab, India
来源：
POLYCYCLIC AROMATIC COMPOUNDS | 2024年 / 44卷 / 07期
关键词：
Diastereo-selectivity; Hetero-Diels alder reactions; beta-Lactams; pi-Facial selectivity; BETA-LACTAMS; INHIBITORS; ACCESS; REGIO;
D O I：
10.1080/10406638.2023.2257844
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reported work presents the diastereo, regio-, and pi-facial selective synthesis of hetero-Diels-Alder (H-DA) cycloadducts with diazene derivatives viz. di-isopropyldiazocarboxylate and diethylazodicarboxylate with cis/trans-3-butadienyl-beta-lactams having stereocentres at its alpha and beta-position. The H-DA reactions resulted in the formation of beta-lactam tethered-3,6-dihydro-pyridazines in good yields.
引用
收藏
页码：4808 / 4815
页数：8
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