Loss of Respiratory Syncytial Virus Antibody Functions During the Peak of the COVID-19 Pandemic Mitigation Measures

被引:2
|
作者
Abu-Raya, Bahaa [1 ,2 ,5 ]
Reicherz, Frederic [1 ,2 ,3 ]
Michalski, Christina [1 ,2 ]
Paramo, Marina Vineta [1 ,2 ]
Majdoubi, Abdelilah [1 ,2 ]
Golding, Liam [1 ,2 ]
Granoski, Madison [4 ]
Stojic, Aleksandra [4 ]
Marchant, David J. [4 ]
Lavoie, Pascal M. [1 ,2 ]
机构
[1] British Columbia Childrens Hosp Res Inst, 950 West 28th Ave, Vancouver, BC V5Z 4H4, Canada
[2] Univ British Columbia, Fac Med, Dept Pediat, Vancouver, BC, Canada
[3] Univ Witten Herdecke, Childrens Hosp Datteln, Dept Pediat, Datteln, Germany
[4] Univ Alberta, Li Ka Shing Inst Virol, Fac Med & Dent, Dept Med Microbiol & Immunol, Edmonton, AB, Canada
[5] Univ British Columbia, Dept Pediat, Vancouver, BC, Canada
关键词
COVID-19; Fc-mediated function; immunity debt; RSV; RSV hiatus; RISK-FACTORS; PROTECTION; INFECTION; INFANTS; LOAD;
D O I
10.1093/jpids/piad099
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Studies have linked respiratory syncytial virus (RSV) antibody-mediated phagocytosis and complement deposition to severe RSV infection in humans. This study shows waning of these antibody functions in women of childbearing age in 2020-2021 during the implementation of COVID-19 mitigation measures, in absence of RSV circulation. These functions could be explored as correlates of protection against severe RSV disease. The waning of phagocytic and complement-mediated antibody functions associated with protection from severe respiratory syncytial virus (RSV) infection in humans, in the absence of viral circulation during the peak of implementation of COVID-19 mitigation measures in 2020-2021 indicate that these functions could be explored as correlates of protection against severe RSV disease.
引用
收藏
页码:642 / 645
页数:4
相关论文
共 50 条
  • [1] RESPIRATORY SYNCYTIAL VIRUS EPIDEMIC DURING THE COVID-19 PANDEMIC
    Cooney, Hannah C.
    Fleming, Catriona
    Scheffer, Ingrid E.
    JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 2022, 58 (01) : 215 - 216
  • [2] Interepidemic Respiratory Syncytial Virus during the COVID-19 Pandemic
    Huang, ChunHong
    Sahoo, Malaya K.
    Verghese, Michelle
    Sibai, Mamdouh
    Solis, Daniel
    Mfuh, Kenji O.
    Kurzer, Jason
    Hogan, Catherine A.
    Doan, Thuy A.
    Pinsky, Benjamin A.
    MICROBIOLOGY SPECTRUM, 2022, 10 (03):
  • [3] Variation in the seasonality of the respiratory syncytial virus during the COVID-19 pandemic
    Lorena Bermúdez Barrezueta
    Vanesa Matías Del Pozo
    Pablo López-Casillas
    Marta Brezmes Raposo
    María Gutiérrez Zamorano
    María de la Asunción Pino Vázquez
    Infection, 2022, 50 : 1001 - 1005
  • [4] Variation in the seasonality of the respiratory syncytial virus during the COVID-19 pandemic
    Bermudez Barrezueta, Lorena
    Matias Del Pozo, Vanesa
    Lopez-Casillas, Pablo
    Brezmes Raposo, Marta
    Gutierrez Zamorano, Maria
    Pino Vazquez, Maria de la Asuncion
    INFECTION, 2022, 50 (04) : 1001 - 1005
  • [5] Resurgence of Respiratory Syncytial Virus Following COVID-19 Pandemic Measures: A Study of Antibody Dynamics in Young Children
    Kennedy, Joshua
    Tilly, Collette
    Chin, Justin
    Frenner, Rachel
    Boyanton, Bobby
    Ingold, Ashton
    Hartzell, Susanna
    Frederick, Dana
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2025, 155 (02) : AB294 - AB294
  • [6] Epidemiology of Respiratory Syncytial Virus in Germany before and during covid-19 pandemic
    Loerch, Svenja
    Erdnuess, Frank
    Reineke, Thorsten
    Frerich, Beate
    Kamin, Wolfgang
    Loerch, Svenja
    EUROPEAN RESPIRATORY JOURNAL, 2023, 62
  • [7] During the COVID-19 pandemic where has respiratory syncytial virus gone?
    Di Mattia, Greta
    Nenna, Raffaella
    Mancino, Enrica
    Rizzo, Valentina
    Pierangeli, Alessandra
    Villani, Alberto
    Midulla, Fabio
    PEDIATRIC PULMONOLOGY, 2021, 56 (10) : 3106 - 3109
  • [8] COVID-19 public health measures and respiratory syncytial virus
    Britton, Philip N.
    Hu, Nan
    Saravanos, Gemma
    Shrapnel, Jane
    Davis, Jake
    Snelling, Tom
    Dalby-Payne, Jacqui
    Kesson, Alison M.
    Wood, Nicholas
    Macartney, Kristine
    McCullagh, Cheryl
    Lingam, Raghu
    LANCET CHILD & ADOLESCENT HEALTH, 2020, 4 (11): : E42 - E43
  • [9] Severe Respiratory Syncytial Virus Infections in Elderly Persons During the COVID-19 Pandemic
    Shimada, Daishi
    Seki, Masafumi
    INFECTION AND DRUG RESISTANCE, 2024, 17 : 3669 - 3675
  • [10] Shifting Epidemiology and Severity of Respiratory Syncytial Virus in Children During the COVID-19 Pandemic
    Rao, Suchitra
    Armistead, Isaac
    Messacar, Kevin
    Alden, Nisha B. B.
    Schmoll, Emma
    Austin, Elizabeth
    Dominguez, Samuel R. R.
    JAMA PEDIATRICS, 2023, 177 (07) : 730 - 732