Contrasting Features of T-Cell Expansion in Classical Hodgkin Lymphoma: Tumor Microenvironment Vs. Peripheral Blood and before Vs. during Anti-PD1 Treatment

被引：0
|
作者：
Seifert, Nicole [1 ]
Reinke, Sarah [2 ]
Grund, Johanna [2 ]
Mueller-Meinhard, Berit [2 ]
Engert, Andreas [3 ]
Borchmann, Peter [4 ,5 ,6 ]
Broeckelmann, Paul J. [3 ]
Altenbuchinger, Michael [1 ]
Klapper, Wolfram [2 ]
机构：
[1] Univ Med Ctr Gottingen, Dept Med Bioinformat, Gottingen, Germany
[2] Univ Hosp Schleswig Holstein, Dept Pathol, Kiel, Germany
[3] Univ Hosp Cologne, Dept Internal Med, Cologne, Germany
[4] German Hodgkin Study Grp, Cologne, Germany
[5] Univ Cologne, Fac Med, Dept Internal Med, Ctr Integrated Oncol Aachen Bonn Cologne Dusseldo, Cologne, Germany
[6] Univ Hosp Cologne, Cologne, Germany
来源：
BLOOD | 2023年 / 142卷
关键词：
D O I：
10.1182/blood-2023-186527
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：4
相关论文
共 19 条
  • [1] Lymphoma tumor burden before chimeric antigen receptor T-Cell treatment: RECIL vs. Lugano vs. metabolic tumor assessment
    Winkelmann, Michael
    Buecklein, Veit L.
    Blumenberg, Viktoria
    Rejeski, Kai
    Ruzicka, Michael
    Unterrainer, Marcus
    Schmidt, Christian
    Dekorsy, Franziska J.
    Bartenstein, Peter
    Ricke, Jens
    Von Bergwelt-Baildon, Michael
    Subklewe, Marion
    Kunz, Wolfgang G.
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [2] Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1
    Reinke, Sarah
    Broeckelmann, Paul J.
    Iaccarino, Ingram
    Garcia-Marquez, Maria
    Borchmann, Sven
    Jochims, Franziska
    Kotrova, Michaela
    Pal, Karol
    Brueggemann, Monika
    Hartmann, Elena
    Sasse, Stephanie
    Kobe, Carsten
    Mathas, Stephan
    Soekler, Martin
    Keller, Ulrich
    Bormann, Matthias
    Zimmermann, Andreas
    Richter, Julia
    Fuchs, Michael
    von Tresckow, Bastian
    Borchmann, Peter
    Schloesser, Hans
    von Bergwelt-Baildon, Michael
    Rosenwald, Andreas
    Engert, Andreas
    Klapper, Wolfram
    BLOOD, 2020, 136 (25) : 2851 - 2863
  • [3] Peripheral T-cell lymphoma not otherwise specified vs. Hodgkin's lymphoma on fine needle aspiration cytology
    Mathur, S
    Verma, K
    ACTA CYTOLOGICA, 2005, 49 (04) : 373 - 377
  • [4] T-cell diversity and exclusion of blood-derived T-cells in the tumor microenvironment of classical Hodgkin Lymphoma
    Seifert, Nicole
    Reinke, Sarah
    Grund, Johanna
    Mueller-Meinhard, Berit
    Richter, Julia
    Heilmann, Thorsten
    Schloesser, Hans
    Kotrova, Michaela
    Brueggemann, Monika
    Borchmann, Peter
    Broeckelmann, Paul J.
    Altenbuchinger, Michael
    Klapper, Wolfram
    LEUKEMIA, 2025, 39 (03) : 684 - 693
  • [5] Programmed cell death protein1 (PD1)-expression in the microenvironment of classical Hodgkin lymphoma at relapse after conventional chemotherapy and at relapse on anti-PD1 treatment
    Sasse, Stephanie
    Reddemann, Katharina
    Diepstra, Arjan
    Borchmann, Sven
    Oschlies, Ilske
    Schnitter, Antje
    Engert, Andreas
    Borchmann, Peter
    Klapper, Wolfram
    HAEMATOLOGICA, 2019, 104 (01) : E45 - E46
  • [6] Programmed cell death protein-1 (PD-1)-expression in the microenvironment of classical Hodgkin lymphoma at relapse during anti-PD-1-treatment
    Sasse, Stephanie
    Reddemann, Katharina
    Diepstra, Arjan
    Oschlies, Ilske
    Schnitter, Antje
    Borchmann, Sven
    Engert, Andreas
    Borchmann, Peter
    Klapper, Wolfram
    HAEMATOLOGICA, 2019, 104 (01) : E21 - E24
  • [7] PD-L1 dominated tumor-CAF-immune cell crosstalk of stromal microenvironment: Endometrial tumor vs. tumor-adjacent normal
    Lin, Xiaoqian
    Aske, Jennifer
    Dale, Adam
    Koirala, Nischal
    Thompson, Ethan
    Fagerness, Mary
    Flier, Natasha
    Davies, Paige
    Kehoe, Stacy
    Ageton, Cheryl
    Gaster, Kris
    Espaillat, Luis Rojas
    Starks, David
    Sulaiman, Raed
    De, Pradip
    Dey, Nandini
    CANCER RESEARCH, 2022, 82 (12)
  • [8] A multicenter retrospective study on the real-world outcomes of autologous vs. allogeneic hematopoietic stem cell transplantation for peripheral T-cell lymphoma in China
    Gu, Zhen-Yang
    Dong, Yu-Jun
    Fu, Xiao-Rui
    Li, Nai-Nong
    Liu, Yao
    Wu, Xiao-Xiong
    Wang, Yi-Ni
    Li, Yu-Hang
    Ren, Han-Yun
    Zhang, Ming-Zhi
    Li, Xiao-Fan
    Wang, Mai-Hong
    Wu, Ya-Mei
    Liu, Dai-Hong
    Wang, Zhao
    Hu, Liang-Ding
    Huang, Wen-Rong
    CHINESE MEDICAL JOURNAL, 2021, 134 (13) : 1584 - 1592
  • [9] Differential Outcome of Patients with Primary Refractory Vs. Relapsed Peripheral T-Cell Lymphoma: Analysis from a Prospective Multicenter US Cohort Study
    Lansigan, Frederick
    Horwitz, Steven M.
    Pinter-Brown, Lauren C.
    Carson, Kenneth R.
    Shustov, Andrei R.
    Rosen, Steven T.
    Pro, Barbara
    Hsi, Eric D.
    Federico, Massimo
    Gisselbrecht, Christian
    Schwartz, Marc
    Bellm, Lisa A.
    Acosta, Mark
    Foss, Francine M.
    BLOOD, 2016, 128 (22)
  • [10] Differential Changes in Inflammatory Mononuclear Phagocyte and T-Cell Profiles within Psoriatic Skin during Treatment with Guselkumab vs. Secukinumab
    Mehta, Heena
    Mashiko, Shunya
    Angsana, Julianty
    Rubio, Manuel
    Hsieh, Ya-Ching M.
    Maari, Catherine
    Reich, Kristian
    Blauvelt, Andrew
    Bissonnette, Robert
    Munoz-Elias, Ernesto J.
    Sarfati, Marika
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021, 141 (07) : 1707 - +
12