ULTRA-FLEXIBLE MULTICHANNEL NEURAL MICROELECTRODES MODIFIED BY PEDOT:PSS/IROX FOR ENHANCED SENSING AND LOCALIZED STIMULATION

被引:0
|
作者
Jiang, Wanqi [1 ,2 ]
Wang, Xueying [1 ,2 ]
Yang, Huiran [1 ]
Zou, Dujuan [1 ,2 ]
Tao, Chen [1 ,3 ]
Zhu, Ziyi [1 ,2 ]
Jiang, Jianbo [1 ,2 ]
Zhou, Zhitao [1 ,2 ]
Sun, Liuyang [2 ,4 ]
Tao, Tiger H. [1 ,2 ,3 ,4 ,5 ,6 ,7 ,8 ,9 ]
Wei, Xiaoling [1 ,2 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Microsyst & Informat Technol, State Key Lab Transducer Technol, Shanghai, Peoples R China
[2] Univ Chinese Acad Sci, Beijing, Peoples R China
[3] Shanghai Tech Univ, Sch Phys Sci & Technol, Shanghai, Peoples R China
[4] Chinese Acad Sci, Shanghai Inst Microsyst & Informat Technol, 2020 X Lab, Shanghai, Peoples R China
[5] Univ Chinese Acad Sci, Ctr Mat Sci & Optoelect Engn, Beijing, Peoples R China
[6] Chinese Acad Sci, Ctr Excellence Brain Sci & Intelligence Technol, Shanghai, Peoples R China
[7] Neuroxess Co Ltd Jiangxi, Nanchang, Jiangxi, Peoples R China
[8] Guangdong Inst Intelligence Sci & Technol, Zhuhai, Guangdong, Peoples R China
[9] Tianqiao & Chrissy Chen Inst Translat Res, Shanghai, Peoples R China
基金
国家重点研发计划; 中国国家自然科学基金;
关键词
intracortical microelectrode; flexible probe; neural electrophysiological signal detection; stimulation;
D O I
10.1109/MEMS58180.2024.10439326
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
We report an ultra-flexible multi-channel neural electrode with a novel modified approach to achieve the performance of high charge storage capacity. This kind of neural electrodes possess the thickness of similar to 2.5 mu m, the width of similar to 100 mu m, and bending stiffness of similar to 3.9x10(-13) N center dot m(2), which testify to its outstanding flexibility, higher biocompatibility and working stability. Moreover, ultrathin flexible neural electrode modified with PEDOT: PSS/IrOx has a high charge storage capacity of similar to 24.2 mC/cm(2), which is similar to 27.9 times and similar to 1.6 times of PEDOT:PSS and IrOx alone, presenting superior performance in electrical stimulation. The extremely thin thickness and modified nanomaterials both benefit longterm high-quality neurophysiological signal recording. By implanting the ultraflexible neural electrode, it was verified that the modified electrode had long-term stable signal recording ability for 6 weeks and good localized electrical stimulation effect, which demonstrated to be a powerful tool for the research of brain neuroscience.
引用
收藏
页码:318 / 321
页数:4
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