Light-Driven Photocatalyst-Free Synthesis of β, δ-Functionalized Ketones from Aldehydes

被引：0
|
作者：
Mou, Quansheng [1 ]
Han, Tongyu [1 ]
Tian, Miao [1 ]
Liu, Mingxin [1 ]
机构：
[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 07期
关键词：
ARYL KETONES; PHOTOCHEMISTRY; BENZALDEHYDE;
D O I：
10.1021/acs.joc.4c00125
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of ketones has been a long focus of chemistry research, on account of its unique reactivity. Herein, we report a simple light-driven photocatalyst-free synthesis of beta, delta-functionalized ketones from aldehydes, using inexpensive and commercially abundant feedstock chemicals. This reaction is enabled by the direct acyl radical generation via hydrogen atom transfer and the subsequent radical addition process, avoiding the need for prefunctionalized substrates and organometallic reagent.
引用
收藏
页码：5189 / 5199
页数：11
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