Nicotinamide Phosphoribosyltransferase (Nampt)-dependent Redox Metabolism is Indispensable for Growth Plate Chondrocyte Survival and Skeletal Development

被引:0
|
作者
Warren, Aaron [1 ]
Ali, Mohsin [1 ]
Marques-Carvalho, Adriana [1 ,2 ]
Reyes-Castro, Olivia [1 ]
Kim, Ha-Neui [1 ]
Porter, Ryan [1 ]
O'Brien, Charles [1 ]
Nookaew, Intawat [1 ]
Morello, Roy [1 ]
Almeida, Maria [1 ]
机构
[1] Univ Arkansas Med Sci, Little Rock, AR USA
[2] Univ Coimbra, Ctr Neurosci & Cell Biol, Coimbra, Portugal
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1083
引用
收藏
页码:28 / 28
页数:1
相关论文
共 3 条
  • [1] Pharmacological inhibition of nicotinamide adenine dinucleotide (NAD plus ) production enzyme nicotinamide phosphoribosyltransferase (NAMPT) impairs cellular survival, energy metabolism, and tumor growth in neuroblastoma (NB) models
    Varriano, Sophia
    Lee, Unsun
    Collins, Victor
    Nguyen, Rosa
    Issaq, Sameer
    Sun, Ming
    Nelson, Ariana
    Yeung, Choh
    Thomas, Craig
    Mendoza, Arnulfo
    Thiele, Carol
    Heske, Christine
    MOLECULAR CANCER THERAPEUTICS, 2023, 22 (12)
  • [2] Chondrocyte-specific Knockout of Cbfβ Reveals the Indispensable Function of Cbfβ in Chondrocyte Maturation, Growth Plate Development and Trabecular Bone Formation in Mice
    Wu, Mengrui
    Li, Yi-Ping
    Zhu, Guochun
    Lu, Yun
    Wang, Yiping
    Jules, Joel
    McConnell, Matthew
    Serra, Rosa
    Shao, Jian-Zhong
    Chen, Wei
    INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2014, 10 (08): : 861 - 872
  • [3] Nutrition-dependent stunted growth in neonatal mice is associated with decreased chondrocyte proliferation but not the activity of skeletal stem cells within the growth plate
    Schnyder, Daniela
    Usanova, Anna
    Zhou, Baoyi
    Heinonen, Jussi
    Lopez-Pedrosa, Jose M.
    Rueda, Ricardo
    Chagin, Andrei S.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2023, 38 : 117 - 118