Systematic evaluation of the diagnostic morphological features of submucosal tumors (SMTs) in the stomach. The Chi-nese and English-related clinical research literature published in Chinese and English databases (including PubMed, SinoMed, EMBASE, CNKI, Wanfang, VIP, etc.) from January 2000 to November 2022 were searched. Two researchers independently completed literature screening, content extraction, literature quality assessment, and RCT bias risk, and a meta-analysis was performed using Review Manager 5.3 software in Cochrane. A total of 8 literatures were included, including 1175 patients with SMTs, including 597 GIST, 274 leiomyomas, 2 granulosa cell tumors, 143 ectopic pancreases, 31 cysts, 9 schwannomas, 66 lipoma, and 53 others. Four English and four Chinese literatures were included, and three of the selective results were reported as high risk. The results of the meta-analysis showed significant differences in the shape characteristics, tumor size, echo characteristics, and origin level characteristics of SMTs patients with different diseases (P < 0.05). However, imaging diagnostic efficacy was higher, and there was little difference in imaging diagnos-tic efficacy among SMTs patients with other conditions (P > 0 �05). Current evidence indicates that imaging techniques IP 203.8 109 20 On: T , 27 Jun 2023 11 2742 have high diagnostic efficiency in the identification and diagnosis of SMTs diseases, and morphological heterogeneity is Copyright: American Scientific Publishers present in different conditions.