Effects of mexiletine on a race-specific mutation in Nav1.5 associated with long QT syndrome

被引：0
|
作者：
Wu, Xin [1 ]
Li, Yawei [2 ]
Hong, Liang [3 ]
机构：
[1] Univ Illinois, Chicago, IL USA
[2] Northwestern Univ, Chicago, IL USA
[3] Univ Illinois, Div Cardiol, Chicago, IL USA
来源：
BIOPHYSICAL JOURNAL | 2023年 / 122卷 / 03期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
494-Pos
引用
收藏
页码：100A / 100A
页数：1
相关论文
共 50 条
  • [1] Effects of Mexiletine on a Race-specific Mutation in Nav1.5 Associated With Long QT Syndrome
    Wu, Xin
    Li, Yawei
    Hong, Liang
    FRONTIERS IN PHYSIOLOGY, 2022, 13
  • [2] Mutation in Nav1.5 Associated with Brugada Syndrome - a Mutational Hotspot?
    Schmitt, Nicole
    Calloe, Kirstine
    Veltmann, Christian
    Pfeiffer, Ryan
    Borggrefe, Martin
    Wolpert, Christian
    Schimpf, Rainer
    Cordeiro, Jonathan M.
    Antzelevitch, Charles
    BIOPHYSICAL JOURNAL, 2010, 98 (03) : 311A - 311A
  • [3] Abdominal symptoms in patients with long QT syndrome and a "gain of function" mutation in the Nav1.5 sodium channel
    Braak, Breg
    Klooker, Tamira K.
    Scholvinck, Dirk
    Hofman, Nynke
    Wilde, Arthur
    Boeckxstaens, Guy E.
    GASTROENTEROLOGY, 2008, 134 (04) : A683 - A683
  • [4] Differential Thermosensitivity in Nav1.5 Mutations Associated with Long QT and Brugada Syndromes
    Abdelsayed, Mena
    Ruben, Peter C.
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 327A - 328A
  • [5] Nadolol Block of Nav1.5 Does Not Explain Its Efficacy in the Long QT Syndrome
    Besana, Alessandra
    Wang, Dao W.
    George, Alfred L., Jr.
    Schwartz, Peter J.
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2012, 59 (03) : 249 - 253
  • [6] A novel SCN5A mutation associated with the linker between III and IV domains of Nav1.5 in a neonate with fatal long QT syndrome
    Yamamura, Kenichiro
    Muneuchi, Jun
    Uike, Kiyoshi
    Ikeda, Kazuyuki
    Inoue, Hirosuke
    Takahata, Yasushi
    Shiokawa, Yuichi
    Yoshikane, Yukako
    Makiyama, Takeru
    Horie, Minoru
    Hara, Toshiro
    INTERNATIONAL JOURNAL OF CARDIOLOGY, 2010, 145 (01) : 61 - 64
  • [7] Calmodulin Mutation Associated With Neonatal Long-QT Syndrome Evokes Increased Persistent Sodium Current From a Fetal Nav1.5 Splice Variant
    Murphy, Lisa L.
    Campbell, Courtney M.
    Crotti, Lia
    Johnson, Christopher N.
    Kunic, Jennifer D.
    Schwartz, Peter J.
    Chazin, Walter J.
    George, Alfred L.
    CIRCULATION, 2013, 128 (22)
  • [8] Nav1.5/R1193Q polymorphism is associated with both long QT and Brugada syndromes
    Huang, H
    Zhao, J
    Barrane, FZ
    Champagne, J
    Chahine, M
    CANADIAN JOURNAL OF CARDIOLOGY, 2006, 22 (04) : 309 - 313
  • [9] Characterization of a novel Nav1.5 channel mutation, A551T, associated with Brugada syndrome
    Chiang, Kun-Chi
    Lai, Ling-Ping
    Shieh, Ru-Chi
    JOURNAL OF BIOMEDICAL SCIENCE, 2009, 16
  • [10] Characterization of a novel Nav1.5 channel mutation, A551T, associated with Brugada syndrome
    Kun-Chi Chiang
    Ling-Ping Lai
    Ru-Chi Shieh
    Journal of Biomedical Science, 16
12345