Contact Tracing and Tuberculosis Preventive Therapy for Household Child Contacts of Pulmonary Tuberculosis Patients in the Kyrgyz Republic: How Well Are We Doing?

被引:2
|
作者
Kadyrov, Meder [1 ]
Thekkur, Pruthu [2 ]
Geliukh, Evgenia [3 ]
Sargsyan, Aelita [4 ]
Goncharova, Olga [1 ]
Kulzhabaeva, Aizat [5 ]
Kadyrov, Asel [6 ]
Khogali, Mohammed [7 ]
Harries, Anthony D. [2 ,8 ]
Kadyrov, Abdullaat [1 ]
机构
[1] Minist Hlth, Natl Ctr Phthisiol, Bishkek 720000, Kyrgyzstan
[2] Int Union TB & Lung Dis, Ctr Operat Res, 2 Rue Jean Lantier, F-75001 Paris, France
[3] Int Charitable Fdn Alliance Publ Hlth, UA-01601 Kiev, Ukraine
[4] TB Res & Prevent Ctr TBRPC, Yerevan 0014, Armenia
[5] Publ Fdn KNCV KG, Bishkek 720000, Kyrgyzstan
[6] Primary Healthcare Ctr 1, Bishkek 720000, Kyrgyzstan
[7] United Arab Emirates Univ UAEU, Inst Publ Hlth IPH, Coll Med & Hlth Sci CMHS, Al Ain 15551, U Arab Emirates
[8] London Sch Hyg & Trop Med, Fac Infect & Trop Dis, Dept Clin Res, London WC1E 7HT, England
关键词
contact investigation; household contact management; childhood TB; pediatric TB; isoniazid preventive therapy; structured operational research training initiative (SORT IT); operational research; INFECTION; BARRIERS; DISEASE;
D O I
10.3390/tropicalmed8070332
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Early identification, screening and investigation for tuberculosis (TB), and provision of TB preventive therapy (TPT), reduces risk of TB among child household contacts of pulmonary TB patients (index patients). A cohort study was conducted to describe the care cascade and timeliness of contact tracing and TPT initiation among child household contacts (aged < 15 years) of index patients initiated on TB treatment in Bishkek, the Kyrgyz Republic during October 2021-September 2022. In the register, information on the number of child household contacts was available for 153 (18%) of 873 index patients. Of 297 child household contacts identified, data were available for 285, of whom 261 (92%) were screened for TB. More than 50% were screened after 1 month of the index patient initiating TB treatment. TB was diagnosed in 23/285 (9%, 95% CI: 6-13%) children. Of 238 TB-free children, 130 (55%) were eligible for TPT. Of the latter, 64 (49%) were initiated on TPT, of whom 52 (81%) completed TPT. While TPT completion was excellent, there was deficiency in contact identification, timely screening and TPT initiation. Thus, healthcare providers should diligently request and record details of child household contacts, adhere to contact tracing timelines and counsel caregivers regarding TPT.
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页数:14
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