ZnO nanoparticles (NPs) have shown high potential in various antibacterial applications. This study greenly synthesized ZnO NPs at different sizes using Paederia lanuginosa aqueous leaf extract and active compounds in Paederia lanuginosa ethanol extract were incorporated into the ZnO NPs to form different ZnO-extract nanoformulations. Chemical methods, FeSEM, UV-Vis, FTIR, EDX spectra, XRD, DLS, and TGA were used to characterize the synthesized extracts, ZnO NPs, and their nanoformulations. The results show that the ZnO NPs had the size of 20-30, 50-70, or 100-150 nm. Organic substances including phenolics, glycosides, and iridoids were present in the nanoformulations. The nanoformulations enlarge the inhibition zone of ZnO nanoparticles against E. coli ATCC 25922 and are potential for antibacterial applications. [GRAPHICS] .
