Optimisation of seed oil and powder of Momordica charantia in the formulation of body scrub cream

被引:0
|
作者
Winarti, Lina [1 ]
Dzakkiyah, Shifwatu [1 ]
Irawan, Eka Deddy [1 ]
Narulita, Erlia [2 ]
机构
[1] Univ Jember, Dept Pharmaceut, Fac Pharm, Jember, Indonesia
[2] Univ Jember, Dept Biol Educ, Jember, Indonesia
来源
PHARMACY EDUCATION | 2023年 / 23卷 / 04期
关键词
Body scrub; Cream; Momordica charantia; Simplex lattice design;
D O I
10.46542/pe.2023.234.127131
中图分类号
G40 [教育学];
学科分类号
040101 ; 120403 ;
摘要
Background: Momordica charantia seed oil and powder are potential ingredients for a body scrub. The seeds contain fatty acids to moisturise the skin, and the mineral content to remove dead skin cells and nourish the skin. Objective: To determine the optimal efficiency of Momordica charantia seed oil and powder on body scrub cream produce. Methods: The body scrub used W/O (water-in-Oil) cream base. Simplex Lattice Design was used to determine five formulas. The irritation test with the Draize Skin Test method was carried out on rats (n = three, in each formula), and the Primary Dermal Irritation Index (PDII) was calculated. Informed consent from the female participants has been obtained for the hedonic test. Results: The body scrub cream produced appropriate organoleptic, was not irritating, and was stable after centrifugation and cycling test. The optimum formula contained five grams of oil and one gram of powder with a pH of 5.21; viscosity of 205.33 dPa.s; spreading of 6.12cm; adhesion time of 19.86 seconds; rate of washing of 20.60 seconds; a colour value of 4.04; scent value of 2.90; and texture value of 2.98. Conclusion: The optimised body scrub cream yielded a good formula which can be developed as a body scrub preparation.
引用
收藏
页码:127 / 131
页数:5
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