The culture of professional degree graduate students is a new form of postgraduate education in China. It focuses on cultivating high-level and applied talents compared with original academic degree graduate students. Considering about the source of full-time professional degree graduate students in domain of software engineering and the current college educational system, this paper makes a few beneficial explorations about curriculum, practice teaching, process management and puts forward the mode and method to improve full-time professional degree graduate education in domain of Software Engineering.