DNA cleavage mediated by water-soluble manganese corrole

被引：0
|
作者：
Jun Lu~a
机构：
来源：
Chinese Chemical Letters | 2011年 / 22卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Corrole; Manganese; DNA; Oxidative cleavage;
D O I：
暂无
中图分类号：
Q523 [脱氧核糖核酸（DNA）];
学科分类号：
071010 ; 081704 ;
摘要：
The DNA nuclease-like activity of a water soluble manganese corrole 5,10,15-tris(N-methyl-4-pyridyl)- corrolatomanganese (Ⅲ)(Mn~ⅢTMPyC) has been investigated.Mn~ⅢTMPyC may bind strongly to DNA via outside groove binding mode as indicated by absorption spectra,viscosity measurements and CD spectra.Mn~ⅢTMPyC exhibited excellent catalytic activity in the DNA oxidative cleavage in the presence of hydroperoxide.
引用
收藏
页码：101 / 104
页数：4
相关论文
共 50 条
  • [1] DNA cleavage mediated by water-soluble manganese corrole
    Lu, Jun
    Liu, Hai Yang
    Shi, Lei
    Wang, Xiang Li
    Ying, Xiao
    Zhang, Lei
    Ji, Liang Nian
    Zang, Lin Quan
    Chang, Chi K.
    CHINESE CHEMICAL LETTERS, 2011, 22 (01) : 101 - 104
  • [2] DNA Binding and Oxidative Cleavage by a Water-soluble Carboxyl Manganese(III) Corrole
    Zhang, Yang
    Wang, Qi
    Wen, Jinyan
    Wang, Xiangli
    Mahmood, Mian H. R.
    Ji, Liangnian
    Liu, Haiyang
    CHINESE JOURNAL OF CHEMISTRY, 2013, 31 (10) : 1321 - 1328
  • [3] Oxidative DNA Cleavage Mediated by Water-soluble Carboxyl Iron(III) Corrole
    Zhang Yang
    Chen Huan
    Wen Jin-Yan
    Wang Xiang-Li
    Wang Hui
    Ji Liang-Nian
    Liu Hai-Yang
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2013, 34 (11): : 2462 - 2469
  • [4] Oxidative DNA cleavage mediated by water-soluble carboxyl iron(III) corrole
    Zhang, Yang
    Chen, Huan
    Wen, Jin-Yan
    Wang, Xiang-Li
    Wang, Hui
    Ji, Liang-Nian
    Liu, Hai-Yang
    Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities, 2013, 34 (11): : 2462 - 2469
  • [5] DNA binding and nuclease activity of a water-soluble sulfonated manganese(III) corrole
    Huang, Jun-Teng
    Wang, Xiang-Li
    Zhang, Yang
    Mahmood, Mian H. R.
    Huang, Yan-Yuan
    Ying, Xiao
    Ji, Liang-Nian
    Liu, Hai-Yang
    TRANSITION METAL CHEMISTRY, 2013, 38 (03) : 283 - 289
  • [6] DNA binding and nuclease activity of a water-soluble sulfonated manganese(III) corrole
    Jun-Teng Huang
    Xiang-Li Wang
    Yang Zhang
    Mian HR Mahmood
    Yan-Yuan Huang
    Xiao Ying
    Liang-Nian Ji
    Hai-Yang Liu
    Transition Metal Chemistry, 2013, 38 : 283 - 289
  • [7] A Highly Emissive Water-Soluble Phosphorus Corrole
    Naitana, Mario L.
    Nardis, Sara
    Pomarico, Giuseppe
    Raggio, Michele
    Caroleo, Fabrizio
    Cicero, Daniel O.
    Lentini, Sara
    Prodi, Luca
    Genovese, Damiano
    Mitta, Saisameera
    Sgarlata, Anna
    Fanfoni, Massimo
    Persichetti, Luca
    Paolesse, Roberto
    CHEMISTRY-A EUROPEAN JOURNAL, 2017, 23 (04) : 905 - 916
  • [8] Manganese water-soluble porphyrin senses DNA conformation
    Di Mauro, E
    Saladino, R
    Tagliatesta, P
    De Sanctis, V
    Negri, R
    JOURNAL OF MOLECULAR BIOLOGY, 1998, 282 (01) : 43 - 57
  • [9] NUCLEASE ACTIVITY OF A WATER-SOLUBLE MANGANESE PORPHYRIN ASSOCIATED WITH POTASSIUM HYDROGEN PERSULFATE - OXIDATIVE CLEAVAGE OF DNA
    FOUQUET, E
    PRATVIEL, G
    BERNADOU, J
    MEUNIER, B
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (15) : 1169 - 1171
  • [10] Water-soluble Manganese and Iron Mesotetrakis(carboxyl)porphyrin: DNA Binding, Oxidative Cleavage, and Cytotoxic Activities
    Shi, Lei
    Jiang, Yi-Yu
    Jiang, Tao
    Yin, Wei
    Yang, Jian-Ping
    Cao, Man-Li
    Fang, Yu-Qi
    Liu, Hai-Yang
    MOLECULES, 2017, 22 (07):
12345