Synthesis and Characterization of Chitosan-g-poly- (D, L-lactic acid) Copolymer

被引：1
|
作者：
Hua YANG?
机构：
来源：
Chinese Chemical Letters | 2005年 / 01期
关键词：
Poly (D; L-lactic acid); chitosan; graft copolymer; coupling; macromolecular initiator;
D O I：
暂无
中图分类号：
O631 [高分子物理和高分子物理化学];
学科分类号：
摘要：
Biodegradable chitosan-g-poly (D, L-lactic acid) copolymers were prepared via two methods. (1) The lactide was grafted onto hydroxyl groups of chitosan by using macromolecular initiator sodium of trimethylsilyl-chitosan, (2) poly (D,L-lactic acid)(PLA) with low molecular weight can be linked to the amino group by coupling activated PLA to trimethylsilyl-chitosan. Two graft copolymers had hydrophilic-hydrophobic character and can be applied as carriers for drug delivery.
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页码：123 / 126
页数：4
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