RANKL-RANK signaling regulates osteoblast differentiation and bone formation

被引:0
|
作者
Xu Cao [1 ]
机构
[1] Department of Orthopedic Surgery, Johns Hopkins University School of Medicine
关键词
RANKL-RANK signaling regulates osteoblast differentiation and bone formation; BMSCs;
D O I
暂无
中图分类号
R68 [骨科学(运动系疾病、矫形外科学)];
学科分类号
1002 ; 100210 ;
摘要
In the recent two decades, it has been well elucidated that receptor activator of nuclear factor-κB ligand (RANKL; also known as TNFSF11) binding to its receptor RANK (also known as TNFRSF11A) drives osteoclast development as the crucial signaling pathway.;However, accumulating evidence also implies that
引用
收藏
页码:426 / 427
页数:2
相关论文
共 50 条
  • [1] RANKL-RANK signaling regulates osteoblast differentiation and bone formation
    Cao, Xu
    BONE RESEARCH, 2018, 6
  • [2] RANKL-RANK signaling regulates osteoblast differentiation and bone formation
    Xu Cao
    Bone Research, 6
  • [3] RANKL-RANK signaling regulates osteoblast differentiation and bone formation
    Xu Cao
    Bone Research, 2018, 6 (04) : 426 - 427
  • [4] RANKL-RANK signaling in osteoclastogenesis and bone disease
    Wada, T
    Nakashima, T
    Hiroshi, N
    Penninger, JM
    TRENDS IN MOLECULAR MEDICINE, 2006, 12 (01) : 17 - 25
  • [5] Possible role of RANKL-RANK signal in osteoblast differentiation.
    Nakamura, Midori
    Yamashita, Teruhito
    Nakamichi, Yuko
    Furuya, Yuriko
    Yasuda, Hisataka
    Udagawa, Nobuyuki
    JOURNAL OF BONE AND MINERAL RESEARCH, 2014, 29 : S163 - S163
  • [6] Discovery of osteoclast differentiation factor, RANKL: inhibition of bone resorption by blocking RANKL-RANK signaling
    Yasuda, H
    JAPANESE JOURNAL OF PHARMACOLOGY, 2002, 88 : 17P - 17P
  • [7] Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system
    Tanaka, S
    Nakamura, K
    Takahasi, N
    Suda, T
    IMMUNOLOGICAL REVIEWS, 2005, 208 : 30 - 49
  • [8] The RANKL-RANK Story
    Nagy, Vanja
    Penninger, Josef M.
    GERONTOLOGY, 2015, 61 (06) : 534 - 542
  • [9] Structural and Functional Insights of RANKL-RANK Interaction and Signaling
    Liu, Changzhen
    Walter, Thomas S.
    Huang, Peng
    Zhang, Shiqian
    Zhu, Xuekai
    Wu, Ying
    Wedderburn, Lucy R.
    Tang, Peifu
    Owens, Raymond J.
    Stuart, David I.
    Ren, Jingshan
    Gao, Bin
    JOURNAL OF IMMUNOLOGY, 2010, 184 (12): : 6910 - 6919
  • [10] The RANKL-RANK Axis: A Bone to Thymus Round Trip
    Sobacchi, Cristina
    Menale, Ciro
    Villa, Anna
    FRONTIERS IN IMMUNOLOGY, 2019, 10