GH/IGF-1轴对肾脏的影响

[1] Acute effect of human recombinant insulin - like growth factor I on renal function in humans. Giordano M,Defronzo RA. Nephron . 1995

[2] Adverse effects of recombinant human insulin -like growth factor I in obese insulin -resistant type II diabetic patients. Jabri N,Schalch DS,Schwartz SL,et al. Diabetes . 1994

[3] Bioactivity of glomerular ultrafiltrate during heavy proteinuria may contribute to renal tubulo - interstitial lesions:evidence for a role for insulin -like growth factor I. Hirschberg R. The Journal of Clinical Investigation . 1996

[4] Insulin -like growth factor I induces mesangial proliferation and increases mRNA and secretion of collagen. Feld SM,Hirschberg R,Artishevsky A,et al. Kidney International . 1995

[5] Glomerulosclerosis in mice transgenic for human insulin -like growth factor - binding protein -. Sophie D,Danielle S. Bruno F,et al. Kidney International . 2000

[6] Stimulation of Na channels by IGF - 1 in A6 cells:Possible role of tyrosine phosphorylation. Gallego M,Chain Q. Marrero M,et al. Journal of the American Society of Nephrology . 1995

[7] Recombinant human growth hormone exacerbates chronic puromycin aminonucleosidenephropathy in rats. Trachtman H,Futterweit S,Schwob N,et al. Kidney International . 1993

[8] Protection against diabetes - induced nephropathy in growth hormone receptor/binding protein gene -disrupted mice. Bellush LL,Doublier S. Holland AN,et al. The Journal of Endocrinology . 2000

[9] Morphological changes in the kidney of dogs chronically exposed to exogenous growth hormone. Molon - Noblot S. Laroque P.Prahalada S. et al. Toxicologic Pathology . 2000

[10] Renal matrix protein mRNA elevated by insulin - like growth factor -I. Haylor J,Johnson T,Nahas M. Journal of the American Society of Nephrology . 1995

[1] Acute effect of human recombinant insulin - like growth factor I on renal function in humans. Giordano M,Defronzo RA. Nephron . 1995

[2] Adverse effects of recombinant human insulin -like growth factor I in obese insulin -resistant type II diabetic patients. Jabri N,Schalch DS,Schwartz SL,et al. Diabetes . 1994

[3] Bioactivity of glomerular ultrafiltrate during heavy proteinuria may contribute to renal tubulo - interstitial lesions:evidence for a role for insulin -like growth factor I. Hirschberg R. The Journal of Clinical Investigation . 1996

[4] Insulin -like growth factor I induces mesangial proliferation and increases mRNA and secretion of collagen. Feld SM,Hirschberg R,Artishevsky A,et al. Kidney International . 1995

[5] Glomerulosclerosis in mice transgenic for human insulin -like growth factor - binding protein -. Sophie D,Danielle S. Bruno F,et al. Kidney International . 2000

[6] Stimulation of Na channels by IGF - 1 in A6 cells:Possible role of tyrosine phosphorylation. Gallego M,Chain Q. Marrero M,et al. Journal of the American Society of Nephrology . 1995

[7] Recombinant human growth hormone exacerbates chronic puromycin aminonucleosidenephropathy in rats. Trachtman H,Futterweit S,Schwob N,et al. Kidney International . 1993

[8] Protection against diabetes - induced nephropathy in growth hormone receptor/binding protein gene -disrupted mice. Bellush LL,Doublier S. Holland AN,et al. The Journal of Endocrinology . 2000

[9] Morphological changes in the kidney of dogs chronically exposed to exogenous growth hormone. Molon - Noblot S. Laroque P.Prahalada S. et al. Toxicologic Pathology . 2000

[10] Renal matrix protein mRNA elevated by insulin - like growth factor -I. Haylor J,Johnson T,Nahas M. Journal of the American Society of Nephrology . 1995