Consecutive Reaction of Bis[2,2,2-trifluoroethyl]phosphite.Onepot Synthesis of Substituted 3-Cyano-β,γ-unsaturated Nitriles with Exclusive or Predominant E-Selectivity

被引：0
|
作者：
沈延昌
张玉明
机构：
[1] State Key Laboratory of Organometallic Chemistry
[2] Shanghai Institute of Organic Chemistry
[3] Chinese Academy of Sciences
[4] Shanghai 200032
[5] China
来源：
Chinese Journal of Chemistry | 2003年 / 07期
基金：
中国国家自然科学基金;
关键词：
consecutive reaction; one-pot synthesis; 3-cyano-β; γ-unsaturated nitrile; bis[2; 2-trifluoroethyl]phosphite; E-selec-tivity;
D O I：
暂无
中图分类号：
O621 [有机化学一般性问题];
学科分类号：
070303 ; 081704 ;
摘要：
The consecutive reaction of bis [2, 2, 2-trifluoroethyl] phosphiteand its application to the one-pot synthesis of 3-cyano-β, γ-un-saturated nitriles with exclusive or predominant E-selectivity(E: Z=100--85:0--15) and excellent yields (94%--99%) aredescribed.
引用
收藏
页码：907 / 909
页数：3
相关论文
共 5 条
  • [1] Consecutive reaction of bis [2,2,2-trifluoroethyl]phosphite.: One-pot synthesis of substituted 3-cyano-β,γ-unsaturated nitriles with exclusive or predominant E-selectivity
    Shen, YC
    Zhang, YM
    CHINESE JOURNAL OF CHEMISTRY, 2003, 21 (07) : 907 - 909
  • [2] SYNTHESIS OF ORGANOFLUORINE BUILDING-BLOCKS .3. AN ELECTROCHEMICAL PREPARATION AND REACTION OF DIMETHYL 2,3-BIS(2,2,2-TRIFLUOROETHYL)SUCCINATE
    UNEYAMA, K
    MAKIO, S
    NANBU, H
    JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (04): : 872 - 877
  • [3] Synthesis of (2,2,2-trifluoroethyl) substituted pyridazin-3(2H)-ones and 1,5-dihydropyrrol-2-ones from α,β-unsaturated γ-lactones and hydrazines
    Mykhaylychenko, Sergiy
    Harakat, Dominique
    Dupas, Georges
    Shermolovich, Yuriy G.
    Bouillon, Jean-Philippe
    JOURNAL OF FLUORINE CHEMISTRY, 2009, 130 (04) : 418 - 427
  • [4] Selective synthesis of cis-alpha,beta-unsaturated sulfoxides and sulfides by the Horner-Wittig reaction with bis(2,2,2-trifluoroethyl)phosphono sulfoxides and aromatic aldehydes
    Kokin, K
    Tsuboi, S
    Motoyoshiya, J
    Hayashi, S
    SYNTHESIS-STUTTGART, 1996, (05): : 637 - &
  • [5] Catalytic Asymmetric Synthesis of Vicinally Bis(trifluoromethyl)-Substituted Molecules via Normal [3+2] Cycloaddition of N-2,2,2-Trifluoroethyl Benzothiophene Ketimines and β-Trifluoromethyl Enones
    Zhao, Jian-Qiang
    Zhang, Xue-Man
    He, Yu-Ying
    Peng, Qiao-Qiao
    Rao, Han-Wen
    Zhang, Yan-Ping
    Wang, Zhen-Hua
    You, Yong
    Yuan, Wei-Cheng
    ORGANIC LETTERS, 2023, 25 (44) : 8027 - 8032
1