全身麻醉术后对中老年病人认知功能的影响

被引:114
|
作者
王春燕
吴新民
机构
[1] 北京大学第一医院麻醉科
[2] 北京大学第一医院麻醉科
[3] 山西医科大学第一医院麻醉科
关键词
麻醉,全身; 术后并发症; 认知障碍;
D O I
暂无
中图分类号
R614.2 [全身麻醉];
学科分类号
摘要
目的 研究全身麻醉对非心脏外科术后认知功能的影响。方法 随机选择40例无神经、精神系统疾病史或服用相应药物的择期非心脏外科手术病人(ASAI-Ⅱ),其中20例施行全身麻醉,20例施行全身麻醉复合硬膜外阻滞,分别就7项认知功能于术前、术后3d和7d进行测定评分。7项测试项目中至少2项,其中单项测试值低于基础值20%以上者即确定为认知功能损害。结果 40例病人术后3d和7d认知功能紊乱发生率分别为65.2%和40%。术后早期认知功能紊乱全麻复合硬膜外阻滞与单纯全麻组间无显著性差异。年龄与术后认知功能测试项目中的视觉再生(γ=-0.49)和钉板试验(γ= 0.49)有相关关系(P<0.05)。结论 非心脏外科手术后病人特别是高龄病人早期存在认知功能紊乱,应当引起临床医生的足够重视。
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页码:12 / 15
页数:4
相关论文
共 14 条
  • [1] Postoperative delirium in the elderly. Parikh SS,Chung F. Anesthesia and Analgesia . 1995
  • [2] Cognitive decline after major noncardiac operations: a prelimingary prospective study. Grichnik KP,Ijsselmuiden AJ,D’Amico TA,et al. The Annals of Thoracic Surgery . 1999
  • [3] Neuropsychological assessment, 3rd edn. Lezak MD. . 1995
  • [4] Risk factors and solutions for the development of neurobehavioral changes after cornary artery bypass grafting. Hammon JW Jr,Stump DA,Kon ND,et al. The Annals of Thoracic Surgery . 1997
  • [5] Predictors of cognitive decline after cardiac operaion. Newman MF,Cogwheel ND,Elemental JA,et al. The Annals of Thoracic Surgery . 1995
  • [6] Cognition after major surgery in the elderly:test performance and complaints. Dijkstra JB,Houx PJ,Jolles J. British Journal of Anaesthesia . 1999
  • [7] Influence of anesthetic methods on mental function. Jones MJ. Acta Chirurgica Scandinavica . 1998
  • [8] Jugular bulb saturation and cognitive dysfunction after cardiopulmonary bypass. Croughwell ND,Newnam MF,Biumenthal JA,et al. The Annals of Thoracic Surgery . 1994
  • [9] Cognitive effects after epidural vs general anaesthesia in old adults: a randomized trail. Williams-Russo P,Sharrock NE,Matis S,et al. The Journal of The American Medical Association . 1995
  • [10] Long-term postoperative cognitive dysfunction in the elderly: ispocdl study. Moller JT,Cluimans P,Rasmussen LS,et al. The Lancet . 1998